444 Comments
Michel's avatar
Lance Grindle's avatar

Thank you Dr MWD for permitting me to collaborate

with the writing of this article.

Dr Lance Grindle, Ecuador

Old_Mainer's avatar

Dr. Grindle,

-Thank you so much for you enormous contribution to this article.

-How do you choose a type/version/brand of hematoxylin that is safe for this purpose? Are you aware of any hazards from the wrong choice?

Lance Grindle's avatar

Old Mainer, You have kindly expressed yourself with the word enormous. Using that word means a lot to myself and MWD who demonstrably did much more hard work than I.

It used to be easier to get Htx from the NY Stain Commission as a new batch appeared. We did not know it at the time but alas those days seem to be cone. I wish I had the foresight to have purchased more. If there is someone reading this that has connections or the possibility of obtaining Htx when a new batch becomes available I would be immensely grateful. I do not know of any hazards of a 'wrong choice' of obtention of Htx but with a disclaimer that I am not versed in knowing if one batch is better or even 'safer' than another, compounded with the fact that Htx is sold as a stain only with no reference nor recommendation of medical use. We filter it of course. dWe have used from six different batches and the clinical results seem to be the same. None has produced toxicity nor in comparison with another. Let us hope that it become easier not harder to get Htx as a result of this substack. That would be a loss for Medicine.

Angela Brooks-Reese's avatar

Hi Lance, Thank you for your contribution to this article. I have read everything I can and I am most interested in your research. Yesterday I started using the D-Hematoxylin on my Mom for metastatic kidney cancer that has created a 5.3 x 4.0 cm tumor in her right lung. I mixed 1/4 teaspoon of hematoxylin into 1/2 teaspoon of 99.9% DMSO in a glass and used 2 drops of this mixture in 3 cm saline solution in her nebulizer. The second dose I used 4 drops. She had quite a bit of coughing and this morning she coughed up a 2 1/4 inch chunk of blood that had been compressed into looking like a bronchial tube. (These scared me until pulmonologist told me how they are formed) and has completely stopped coughing. I nebulized 5 drops of nascent iodine with saline because some fresh blood followed the clot and then after a nap and few hours had passed, gave her two drops of D-hematoxylin in saline.

I tried it first on myself before I used it on my Mom and there was no change in the nebulizer and no effect on me. When Mom used it, the nebulizer turned red, showing us what Dr. Tucker was talking about when he said it only stains the cancer cells.

This is where I got the hematoxylin. Everything I read seems to indicate it is 100% hematoxylin. On the top right of the bottle is says “Chemical Name (%) and right below that it says Hematoxylin (100) CAS517-28-2

https://www.laballey.com/products/hematoxylin-stain

Lance Grindle's avatar

Angela. You asked for a telephone contact number. It could be 001-5932-2-080501 as a landline to our clinic.

Dr Grindle

Angela Brooks-Reese's avatar

Verizon could not verify the phone number, I wanted to be sure I was calling Ecuador.

Is it supposed to be 011?

You can also email me at angela@ma-realtor.com. Thank you!

Angela Brooks-Reese's avatar

Thank you! I will try this number on What’s app tomorrow.

Lance Grindle's avatar

It is not a WhatsApp number. It is a number dialed as a 'long distance number'. It will probably be answered in spanish but they will pass it to me.

From there we could have a short conversation and convene on another better communicatiion means.

Markus's avatar

Dear Dr. Grindle, would you be so kind to contact me markuschaaf@gmail.com ? I would like to ask a few personal questions that I don't want to post publicly.

Angela Brooks-Reese's avatar

001-5932-2-080501 Is this number supposed to start with 011? Verizon told me this number is not valid and should start with 011?

It might be easier to email me at Angela@ma-realtor.com

What is the name of your clinic? Thank you.

Lance Grindle's avatar

I am sorry Angela. You are correct. It is 011 at the beginning not 001 as I wrote. It will work with that.

Angela Brooks-Reese's avatar

Thank you Dr. Grindle, I will use the 011 code when I call.

Before I call, I did email you back.

I gave you the background info so as not to waste any time since I only have 60 minutes via phone.

Once you have received that, I am happy to give you a call.

I’m sure you are very busy and the email is rather long so I don’t mind waiting until you have time to read it. Thank you again, -Angela

Angela Brooks-Reese's avatar

I am trying to get my Global Choice Ecuador activated on my cell phone. I will only have 60 minutes once it is activated.

Old_Mainer's avatar

Dr. Grindle, Do you know of any work using HTX/DMSO to treat chronic lymphocytic leukemia (CLL/SLL)?

Thank you.

Lance Grindle's avatar

Absolutely. If you are asking about publications of D-Htx in CLL, no.

But does it work ? Yes. absolutely. Your note seems like it might be inquiring for someone in particular. I could be wrong though.

Old_Mainer's avatar

Now 82, I was dx w/CLLin 1998, had bendamustine/rituximab in 2015, had venetoclax/rituximab in 2023 and currently have undetectable minimum residual disease (at 1 in 10^4). Would people with experience advise me to use D-Htx now or wait until the dragon rears his head again?

Old_Mainer's avatar

Thank you for your thoughtful reply. Keep up the good work!!

Lance Grindle's avatar

With the information you have provided I would wait-and-see.

Sk4vrddw@protonmail.com's avatar

It is available on Amazon through WnderLand Herbs that says 99+% purity. $99 for a small vial. From China.

WonderLand Herbs Hematoxylin, 5 Grams, CAS 517-28-2, Purity Above 99+% Reference Substance https://a.co/d/9T43vZp

Rich's avatar

The article says researchers mixed powder by weight with liquid by volume, 1:8 g:ml, then dosed by volume ml. No need for those calculations. IMO it doesnt have to be perfect ratio. Tucker's ratio was more powder and obviously worked well, but ecuador researchers found that less worked better. Lance uses lower starting dose than 250mg suggested in the article. More important is to start slow and increase as tolerated. We tried topical 1:8 and had to "rinse it in" with more dmso.

User's avatar
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18 avr.
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Jeff Prager's avatar

I have the Chinese version from Wonderland Herbs and it's Hematoxylin. I spoke with the manufacturer because they have a US warehouse and it's high quality Hematoxylin so I intend to use it.

I don't know how to convert the Hematoxylin powder to mix with liquid DMSO for human use because densities are required. Venice.AI states the following, but these are figures used on mice:

To convert 0.2 milliliters (mL) to milligrams (mg), we need to know the density of the substance in question. Since the density isn't provided, I'll show you the conversion formula and how to use it:

Formula: Mass (mg) = Formula (mL) x Density

Steps: Plug the values into the formula

Identify the density of the substance. For example, the density of water is approximately 1,000 mg/mL (or 1 g/mL).

Plug the values into the formula.

Example (using water):

So, 0.2 mL of water is equivalent to 200 mg. If the substance is not water, you need to use its specific density for an accurate conversion.

END Venice.AI

The density of DMSO is 1.1004 g/mL and the density of Hematoxylin I can't find after a thorough search.

So the question is after determining the right mixture of DMSO + Hematoxylin would multiplying that mixture using 3 pounds for a mouse against my own weight provide a mixture that's viable for treating cancer in humans? Anyone?

User's avatar
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22 juin
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Jeff Prager's avatar

Do not buy from that source, I used this source, same bottle but went to their web sita and bought 5 grams

User's avatar
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22 juin
Comment deleted
Jeff Prager's avatar

I got to from a lab in China, it's pure. I bought 5 grams.

Jeff Prager's avatar

Everything you need to know to mix DMSO and Hematoxylin at the proper doses for human use. I use it but can't tell you whether or not it's working. Yet. Go to pages 171-183.

https://jeffprager.substack.com/p/everything-you-need-to-know-about

KC's avatar

Thank you for your service! I am an extremely healthy 57 yr old with no other medical issues. I have basal cell carcinoma on my lower eyelid. It has permeated the tissues deep enough (all the way through) that I'm being told my only option is a potentially disfiguring surgery. I'd very much like an alternative option!

Do you have any knowledge of, or experience with, using D-hematoxylin for something like this?? I'm in Austin, Texas. I know a practitioner who might be willing to help me make a topical solution according to the instructions in this article if you think it's worth a try.

Any advice is appreciated. I've already sent you an email if you prefer to reply there.

Angela Brooks-Reese's avatar

If you are in a State that allows medical or recreational marijuana, usually you can buy Rick Simpson oil. He discovered it healed cancer from his own basal cell carcinoma on his hand. You can read about Rick Simpson here (he does NOT sell it and is not affiliated with any sites that are using his name to sell it) https://phoenixtears.ca/ I have been using Rick Simpson oil on my Mom for her cancer, I personally know two people that were healed from cancer (esophageal & metastatic breast cancer to the liver). I just started using hematoxylin with DMSO for Mom in the nebulizer for her metastatic kidney cancer spread to the lung.

Rajiv's avatar

I am a physician in the US. Is there a book you would recommend on DMSO?

Lance Grindle's avatar

Certainly. I can initiate. Will send a message in aprox an hour.

Angela Brooks-Reese's avatar

Hi Dr. Grindle. I am using the D-Hematoxylin in a nebulizer for my Mom. She has metastatic kidney cancer (right kidney removed in 2021, no other treatment) that has spread to her lung as of this year (2025). There was a clear CT scan in Jan and a 3.5 cm tumor in March. Now 5.3x4.0 cm as Aug 17. I would like to talk to you or someone in your clinic that has been using this to see if I should change my protocol, or to be able to just ask questions. I am using the protocol I read in the book about Dr. Tucker. Nebulizing 5 drops of D-hematoxylin (mixed 1/4 teaspoon hematoxylin in 1/2 teaspoon of pure DMSO) with 3 ml of saline solution in the nebulizer twice a day. I’ve only been using it for less than a week so far. Thank you for your contribution to this excellent article by Midwestern Doctor.

Jacek Hoffman's avatar

The book: "DMSO, the new healing power"by Morton Walker is available for reading at Internet archive:

https://archive.org/details/dmsonewhealingpo0000walk

A Midwestern Doctor's avatar

Some of the content in that book is not in his 1993 one, but most of it is.

erin's avatar

Doc, I am bewildered. You say that you will tell us how to do non-iv at home in the rest of the article, and then... don't. Did you mean in the rest of the series?

Rich's avatar
22 maiEdited

Everything you need to know to take it orally is in the paid version of the article.

erin's avatar

My question was not about "taking it orally." The doc covered that previously, in detail. My question was about doing it at home for cancer.

Stuart Hutt's avatar

I have the book DMSO in Trauma and Disease by S Jacob and J De La Torre. Which do you think may be more applicable for daily use of DMSO?

Jacek Hoffman's avatar

My language is Polish, so I prefer to use works that have been translated into Polish from various languages, including German. So my recommendations will not be suitable for you.

Isaiah Antares's avatar

Amusing side note: my wife says DMSO makes my breath smell like cucumbers. Even when applied topically. We call it the Magic Cucumber Potion.

Javi Escobar's avatar

Which DMSO you use? And where do you get it from?

Isaiah Antares's avatar

Been using the liquid from here: https://dmsostore.com/collections/dmso-liquid-in-glass-bottle

I have some of their gel too, but have not tried it yet. The liquid works great, even if it stings a bit on the way in.

Gary Morgan's avatar

Again, THANK YOU!

Mrs. Itoldya!'s avatar

You need to be brave & creative to start treating yourself. Dosage suggestions are ALL OVER THE PLACE! I’ve been reading up on Iver, FenBen & DMSO for a few years. Suddenly I’m the one in need. It all started after going to a GI Doc worrying just a bit about distended upper abdomen & unexplained weight gain (substantial!)

A mass showed up in my liver & thickening of colon wall from a CT scan. Bloodwork showed massive thyroid issues & Hashimoto’s a clear diagnosis. Immediately put on Synthroid meds & MRI & colposcopy scheduled for next week.. I’m scared, no doubt, but darn! Been ALL organic for over 5 years. Everything! Sheets, soaps, butter, bread, even beer & everything in between!! No vaccines for 20 years. No medical issues, active & no medications. High quality (expensive!) supplements, yet here I am. I’m sure aging is a factor, but only 65.

So I just dove in! Each day, midday, I take 12mg Iver, 222 mg FenBen & drink 1/2 teaspoon of 70% DMSO, hoping that helps push the Iver & FenBen into my cells. And trying to stay hopeful. Wish me luck & feel free to send prayers!

Mrs. Itoldya!'s avatar

MRI only showed “tiny” benign cysts!! (I’ve had cysts all my life.. ganglion, pilonidal & uterine fibroids cysts, you name it!)

Did my protocol work, who knows. But I’m good. Just one more hurdle, colonoscopy Tuesday 4/29 morning.. 🤞🙏

Steve Carpenter's avatar

I was stage 3 of a very aggressive form of NHL, and did chemo. But at the same time I did 222 mg of Fenben, with breakfast and again with dinner, and Ivermectin @ 16 mg, plus a lot (40ish) of other anti-cancer supplements like resveratrol, and bitter apricot seeds, and no more cancer was detected on my CT scan after 2 months. Good luck! I'm a believer in alternative treatment options.

Mrs. Itoldya!'s avatar

So happy to read this!! And glad you kicked cancer’s butt!! 🙌💪

Dave's avatar

Some amateur thoughts:

•Regarding the cancers dying at the center first the Internet said this:

https://www.cancerresearchuk.org/about-cancer/what-is-cancer/how-cancers-grow

"Blood supply and cancer

As the tumour gets bigger, its centre gets further and further away from the blood vessels in the area where it is growing. So the centre of the tumour gets less and less oxygen and nutrients.

Like healthy cells, cancer cells can't live without oxygen and nutrients. So they send out signals called angiogenic factors. These encourage new blood vessels to grow into the tumour. This is called angiogenesis. Without a blood supply, a tumour can't grow much bigger than a pin head."

•So the cells at the center of the tumor have like zero oxygen which means they become obligate glycolisis using cells and, I read, are pretty crummy at that too. If the hematoxlin interrupts that process they should immediately die of starvation, hence the autolysis. From what I read, apoptosis happens when the cell has energy and autolysis happens when it doesn't since apoptosis is a controlled demolition and autolysis is a building that collapses on its own. So it makes sense that the center mass cells, the absolute most energy deprived, die like this first. And I guess the peripherals still live off of more 'normal' energy processes since they're still in contact with the blood.

•Looking it up, in a really general sense, the first list of cancers this works on are generally less hypoxic and the second list it doesn't work on more hypoxic. Meaning it works on cancers that have better access to oxygen than the cancers that don't have great access to oxygen. Not super straight down the line but it could be that the highly hypoxic (no oxygen all the time) cancers are better adapted to live through CK2 inhibition, and AMD said there are metabolic differences in the CK2 cancers vs the ones less reliant on it.

•I see 'cancer' I think 'how does this fit into the CDR'. D-hematoxylin is certainly not easing the CDR, what with so must death that you can see it in a tube, but maybe these cancer patients are just so damaged there's no other outcome. I've long thought that DMSO could help the CDR by bypassing hardened torpor cell walls which restrict cell functioning in CDR in the first place - maybe D-hematoxylin is pushing the cells along to the CDR3 check for self destruction.

•The fact that D-hematoxylin doesn't seem to work on chronic sources of cancer (stress, vax damage) does imply that it's helping cells get to CDR3 or just killing CDR2 cells. Whereas suramin would stop the extracelluar ATP response and mute cancer CDR spread entirely, if all D-H does is move CDR2 to CDR3 or simply cause CDR2 cells to die (and not stop the move from normal cell->CDR1) then that explains why the cancer just comes back.

Expand full comment
Sherry's avatar

This was an excellent article. Thank you for your time and research.

Janet's avatar

Thank you!

SteveBC's avatar

Thank you, AMWDr. Incredible body of work. :-)

Arabella's avatar

Dear MWD would you consider starting a crowdraising fund to help the research in Ecuador? Just for your subscribers.

Lance Grindle's avatar

Arabella, My comment I believe is immediately above yours.

As context - Dr MWD approached me when he began working on this substack topic.

I am the person (doctor) of the Substack who works in Ecuador.

I began reading all of the commenets and I just encountered yours.

This must be something beyond mere coincidence........

Arabella's avatar

Yes, I did read your comment. Thanks for doing this research. I hope the funding can be organized for you. No one has much spare money right now but we might each have a tiny bit.

Lance Grindle's avatar

I thank you for your suggestion Arabella. Let's see what Life brings here.

Michelle's avatar

Yes, as I was reading, I was wondering if maybe Jeff Childers “Coffee & Covid Army” might be able to fundraise. They’ve easily accumulated donations around $100,000 with everyone pitching in small amounts.

Gary Morgan's avatar

I always look forward to your posts, as well as those from Justus R. Hope at Repurposed Drugs!

David Kukkee's avatar

I have made some notes to pass on to needy folk, AMD. Thank you, to both you and Dr. Grindle for this information.

Denise Grider's avatar

Curious about using DMSO and Methylene Blue topically for skin cancer. My husband has this growth on his head that never heals. I suggested Methylene Blue and the growth went from about 3/4" to 1/4" then he quit using it and the growth took off again. Perhaps using DMSO also would take care of things once and for all.

A Midwestern Doctor's avatar

I have no knowledge on this use of MB

wns115's avatar

Another perspective on MB....Not sure what to believe but this one also seems pretty convincing:: https://chemtrails.substack.com/p/methylene-blue-is-toxic-waste-from

Michelle's avatar

Since same substack (by Agent171311 or something like that) also claims that vitamin D and ivermectin are poison. I think he is controlled opposition.

wns115's avatar

Yes he could be controlled opposition and I like the way you think.

At the same time I try hard not to succumb to cognitive dissonance or refusing to look at any other perspective because it doesn't align with my own beliefs. I try to look at all perspectives and Agent's research is quite fact-based - his methylene blue deep dive was extremely thorough and so is his vitamin D research.

My father is 92 and never took vitamin D and neither did his parents or grandparents all living well into their 90s.

Why has there been such a 'push' for vitamin D since only the early 2000s...mainstream medicine even developed a test to encourage people to take vitamin D ...hmmm - seems fishy to me...

And - why didn't all those people from my fathers heritage struggle without any vitamin d supplements?

Regarding ivermectin, just like all meds, it's a weighing of risk vs benefit. Ivermectin has side effects and my elderly dog died a day after I gave him his heart worm ivermectin med. my holistic vet has advised me NOT to give ivermectin to my dog for heart worm prevention choosing instead diatomaceous earth because of the toxicity.

Food for thought...just looking at all sides

Marcia K.'s avatar

I am not doubting DMSO's abilities for you. But many people use Curaderm BEC5 Cream for skin cancer.

Jan Barendrecht's avatar

The effective ingredients in Curaderm are glycoalkaloids and they cured my SCC rather fast, even when it returned at a different spot. But then on the first spot, instead of SCC there appeared BCC and Curaderm did nothing. I thought increasing the dose might work and used topical potato leave juice which halted growth but didn't heal it. https://www.researchgate.net/publication/311927610_A_Review_of_Occurrence_of_Glycoalkaloids_in_Potato_and_Potato_Products

From there I experimented with DMSO (which has worked miracles on the rest of my body) but only irritates the BCC which then reacts by expanding.

So before "last resort solution" I'll try hematoxylin.

SteveBC's avatar

Jan, try Ivermectin paste on the growth. It works very well on numerous skin growths on my 100yo mother's skin. We have not tried a combination of IVM and DMSO on her growths yet, but I suspect it would improve results, especially on larger growths. On another note, I believe people detox through their head, meaning through their hair follicles when there is hair or through the skin around missing or dead follicles when bald. It might be a good idea to do a detoxification as part of your treatment on the growth. I hope that helps!

Jan Barendrecht's avatar

I have been using ivermectin paste for several months but didn't see any results - other than that there's no negative reaction. No idea how long treatment would have to last before observing a healing effect. Apart from that, the oral treatment is DMSO, fenbendazole, methylene blue and amygdalin. Maybe there's action "from the inside", yet unobservable from the outside, as the BCC surface area is 1.5 sq inch.

With my major food consisting of (raw) fruits, veggies for decades, no need for detox.

Rosie Langridge's avatar

Hoping you find success, but just to mention that most of our toxins are metabolic byproducts, not to mention numerous environmental toxins. So all-round detoxification is always important. Another Substack published an excellent article on it only yesterday. I guess also you could try a different dietary regime.

Jan Barendrecht's avatar

Fasting (no food, just water) for a week is a good check on the level of toxins in your body. Even better when able to measure pH of urine and see if it's (still) transparent instead of becoming opaque.

I did that and the only effect was a decline of physical strength.

That, because my philosophy is to minimize basal metabolism (energy use in rest) without affecting maximum power (strenuous exercise). So there wasn't much of a reserve and detox effects would have been noticed immediately.

SteveBC's avatar

Jan, IVM should show signs of working within a week or less. It isn't working for you. Too bad. Glad to hear you don't need much detoxing! :-)

Jan Barendrecht's avatar

Good to know, thanks Steve. It would be interesting to know the biochemistry of the tumor's self-defense but AFAIK not much of such research exists and I don't have a lab to find out myself.

erin's avatar

Petty spurge latex (one dab for three days) works wonders. Eggplant ground up in apple cider vinegar works too, but slowly.

Jan Barendrecht's avatar

I've used eggplant salves, tinctures and oil infusions on the BCC but without effect. A popular product here with multiple use is "sangre de drago" (dragon's blood) but in my case it only halted progress.

https://www.researchgate.net/publication/8349047_Review_of_Sangre_de_Drago_Croton_lechleri_-_A_South_American_Tree_Sap_in_the_Treatment_of_Diarrhea_Inflammation_Insect_Bites_Viral_Infections_and_Wounds_Traditional_Uses_to_Clinical_Research

paws's avatar

If 'dragon's blood' is another term for bloodroot, fwiw, I've heard there is a facebook group using bloodroot on skin cancers

erin's avatar

Then petty spurge is your plant! Other northern garden spurges might work too. Btw... have you tried just burning it out with 35% hydrogen peroxide? Should not leave a scar. Making a circle around it with vaseline on a q-tip prevents the peroxide from burning normal skin.

Jan Barendrecht's avatar

H2O2 was the very worst I tried. The itch was so strong I needed superpowers to remove it but the harm was done: itching BCC means the cells are expanding / growing at the expense of the surrounding.

erin's avatar

Aha!

Well that I can help with. The itch is a normal reaction to H2O2. Nothing whatsoever to do with cancer -- I have used it extensively for eczema and for ridding myself of small skin bumps. What you do is stick the affected part under running hot water for a few seconds (if inaccessible, try a hot wet rag). Or just tough it out, it calms down in 20-30 minutes. Also, if the 35% seems too irritating, 27% is available in some pool stores. It just takes a bit longer. It too causes the itch, but may be less strong, (27% does not burn normal skin. In my experience.)

Rosie Langridge's avatar

Hi Erin

Does it work on veruccas do you know?

erin's avatar

I don't know. Haven't seen plantar warts mentioned when looking into it.

But since it works on regular warts, it may be worth trying,

I had one when I was a kid. They cut it out after putting some dry ice on it (without anesthesia!) and it did not scar or come back.

Jan Barendrecht's avatar

In my case, H2O2 application did grow the BCC from ~2 cm diameter to 2.5 cm diameter (now it's about 6 cm). 35% H2O2 on the skin only colors it white - for a short time, without any itching, just some irritation.

"One size fits all" is the dogma of big pharma - some people even cured their skin cancer by drinking a nano-silver solution but those are the exceptions, not the rule.

https://www.cancertreatmentsresearch.com/a-silver-bullet-to-kill-cancer/

erin's avatar

I am surprised that it would not have burned out the sick cells. But like you say, every person is different. One's own experimentation is key. 6 cm sounds alarming -- if you do the spurge, please let us know how it goes! (Or the D-hem treatment AMD is referring to.) Whatever works for such a tough lesion should be widely known!

Jan Barendrecht's avatar

There are many alternative skin cancer therapies but indeed have at least to be tested on a healthy skin first and then on small part of lesion. An interesting case was

https://www.researchgate.net/publication/274338503_Management_of_basal_cell_carcinoma_of_the_skin_using_frankincense_Boswellia_sacra_essential_oil_A_case_report

More generally described at

https://www.klinik-st-georg.de/en/boswellia-serrata-frankincense-in-natural-cancer-treatment/

Similar articles can be found re oregano oil.

Jan Barendrecht's avatar

Thanks but I knew that already. Hence the use of (organic) potato leaf juice which can be diluted to the desired concentration (and mixed with DMSO as needed). Egg plant salve, tincture and oil infusion have become so popular they can be bought on eBay (made in USA) at a fraction of the price of Curaderm.

AMD mentioned "trauma" related to possible success of hematoxylin which would apply to me as the start of the SCC and later, BCC was on the spot of an extremely painful impact with piece of metal, years ago. Judging by lifestyle alone, my probability for cancer would be close to zero.

wns115's avatar

Two Feathers black salve healed my skin cancer on my nose. Everyone said it would leave a big hole but it didn't (thankfully!) It healed nicely.

Skin cancer is sometimes an issue caused by fungus/parasites/bacteria in the body. Two Feather cleans out the body and then the final step is to apply topically with a bandaid.

When I did that and pulled the bandaid off several days later, the cancer cells stuck to the bandaid, left a temporary hole in my nose which then closed and healed.

Stuart Hutt's avatar

You may want to check out Dr Andreas Kalcker on Sustack. He lists all his chlorine dioxide protocols including Vaxxx injury. He also has a book Forbidden Health which is an excellent reference. Dr Kalcker does use DMSO with chlorine dioxide with some of his protocols. I have been using chlorine dioxide for about 6 years and am beginning to incorporate DMSO also. My girlfriend and I use a topical spray of chlorine dioxide for skin cancer lesions.

Danbob's avatar

I have a protocol for DMSO+Ivermectin applied topically. Oral ivermectin does not need to be converted into a prodrug in the body and it can be used topically in certain applications. I have patients combine DMSO+IVM to make a paste and apply it to the skin for 30-60 mins 1-3x daily. Right over the tumor location. Wash off. Got a patients surgical path back from a spinal tumor. The result: complete pathological response. Not ghost cells, but back to healthy human cells. I'm currently writing this up for a case study. I use this with keflex for mastitis and flagyl for an odd fragilis felon finger case. We are also discussing leucovorin+dmso for autism.

A Midwestern Doctor's avatar

Thank you so much for sharing this!

Danbob's avatar

You're welcome, but honestly, the credit goes to you. Your work has made me love practicing medicine again. I'm literally treating cancer, successfully, due in large part to your work. Thank you AMD, for all you've done. You are truly my hero!

A Midwestern Doctor's avatar

That's wonderful. If you want to write something synopsizing your experiences, I would be happy to publish it and either have your name on it or have it be an anonymous physician (I have a 217k readers, so that could help you a lot but might also create too much scrutiny, hence your call, although Jason Miller in FL found it only helped him).

Danbob's avatar

I'll have to consider this. (Almost) Everything I do online is anonymous b/c I already have patients beating down my door. What is the best way to get this synopsis in front of you?

Mouzer's avatar

Methylene Blue, which it might help in the short term, also has significant undesireable effects, particularly on brain neurotransmitters. https://www.drugs.com/cons/methylene-blue.html

Marcia K's post. Here is a study on the cream.https://pubmed.ncbi.nlm.nih.gov/1913614/

Cks73's avatar

I had a painful growth in my nose that just wouldn’t heal. I thought it was just a pimple or maybe ingrown hair. After several months of pain I decided to apply 70% DMSO. Within two days the pain was gone but I did not continue and it came back. I restarted and continued for a couple weeks and it completely went away.

Mouzer's avatar

Depends on how long on has been taking it, I read. If you are doing well, good then.

Marcia K.'s avatar

Can you please clarify your response? Not sure which comment it pertains to.

Mouzer's avatar

Denise Grider, the one just above AMD reply.

"Curious about using DMSO and Methylene Blue topically for skin cancer. My husband has this growth on his head that never heals. I suggested Methylene Blue and the growth went from about 3/4" to 1/4" then he quit using it and the growth took off again. Perhaps using DMSO also would take care of things once and for all."

Wayne Kerr's avatar

Excellent article! Thank you so much for the DMSO articles, it has been a game changer! I am also interested on any research or anecdotal info on DMSO and Methylene Blue. Currently I ingest 1-2 tsp of 100% DMSO in RO water. On other days, I ingest 30 mg MB in RO water. Sometimes there is overlap where I ingest the DMSO before I fully clear the MB. I'm curious if these two items can be consolidated and ingested together and if they would have synergistic effects.

scott carl's avatar

I had the exact same question.

Mouzer's avatar

Denise Grider, the one just above AMD reply.

"Curious about using DMSO and Methylene Blue topically for skin cancer. My husband has this growth on his head that never heals. I suggested Methylene Blue and the growth went from about 3/4" to 1/4" then he quit using it and the growth took off again. Perhaps using DMSO also would take care of things once and for all."

Chris's avatar

Dear MWD and Lance, thank you for such detail in describing a great potential cure for cancer that has been suppressed but luckily not forgotten. I can only imagine the hours you put into writing this, and not being in the medical field, I do not understand all the terms used but I must say your writing style and conveying of information makes me want to read on even though I may not need the information for myself as I am healthy. Keep up your great work to benefit the many who can use this information. All the best!

A Midwestern Doctor's avatar

Thank you for your kind words. I try to make this as readable for everyone as I can.

Erik's avatar

Can we get a suggested oral dose in ml/kg for lay users? Teaspoons as suggested in other books isnt good enough

Dave Bross's avatar

First of all...WOW! an amazing article. An incredible number of hours were obviously put in to assemble this. Thanks!

Also thanks to Dr. Grindle for taking that risk to come out in the open.

Second, I suppose the next thing we all want to know is where to source acceptable hematoxylon for home use. Seems like this would be a good one to have in the home health toolkit. I'm guessing finding "clean" hematoxylon is not easily done here in the USA?

A Midwestern Doctor's avatar

All the sources I know of clean sources are sold to professionals and labs. I believe others exists too, but we didn't have the bandwidth to figure out what they were.

Dave Bross's avatar

Yeah, it would take a lot to verify quality.

Dave Bross's avatar

So, naturally curious me went looking, and found this:

https://www.amazon.com/Hematoxylin-517-28-2-Purity-Reference-Substance/dp/B0CR5Y2NBS/ref=sr_1_9?

Not suggesting anyone try this, but, if I was in need and no other options, I would probably try this. The lab analysis they show is over 99% purity but it's also not difficult to lie and post a fake analysis.

All the others I saw on Amazon were very low percentage Hematoxylin, so I definitely wouldn't chance using those.

A Midwestern Doctor's avatar

The only issue is that it's from china so the certificate may be faked.

A Midwestern Doctor's avatar

The only issue is that it's from china :(

Dave Bross's avatar

That was my reason for hesitancy too.

Dave's avatar

I really feel like orally consuming the average hemotoxylin is not gonna be worse than most of the other ineffective chemo and drugs doctors put people on.

Mike H's avatar

I would be willing to bet you are correct Dave.

Lance Grindle's avatar

Thank you Dave for having the sensitivity of your comment about taking the risk for this

wonderful treatment to come out in the open. You have been the only person mentioning

it. If you would like some hematoxylin explain below what you would like to do and I will

be happy to help you with the Htx. [dmso.ozone.md@gmail.com] Lance Grindle

Dave Bross's avatar

Yeah, the risk to reward ratio on this one is quite precarious....so thanks again for being one of the truly courageous ones who takes the huge risks that move us all forward. That level of courage is so rare today...or any day.

Not to worry for the moment, my health is excellent, and there's a low incidence of cancer in my family, but given the toxic soup we've been cursed with living in, you never know.

If I do end up cancerous on some count I'll be back in touch if that's OK with you.

Fred Jewett's avatar

For topical application is the sterilization process necessary or can I simply mix Hematoxylin powder into the DMSO and apply directly? The process of sterilizing, warming, centrifuging makes it more difficult to do at home (but is possible).

Lance Grindle's avatar

No. Not necessary. There is no need to do sterilization process of that part of the process

if it is not going to be used i.v. Rectal also is note needed. Simply mix and apply.

Any questions about preparation, proporciones, administration or other of D-Hematoxylin

anyone in this chat I would be more than happy to answer. Dr Grindle

erin's avatar

Very exciting, Dr Grindle.

For someone wishing to use topically, which product should one order (so it's pure without mordants) and how would you mix a small batch of D-hemoxycilin at home? And how to store afterwards, and how long it keeps once it's mixed. Thank you!

Lance Grindle's avatar

The small batch at home I would mix the pro-rated amount of 1.5 g in 12 ml

of Dmso. But you don't want to mix up that much. MUCH less. You could then

add more dmso to the final solution. It keeps virtually forever. Keep in frig part

of the refrigerator.

erin's avatar

Thank you so much, Doc! So once I mix the strong solution to store, how much should I dilute it to treat, say, a small 1 cm pre-squamous cell lesion?

Lance Grindle's avatar

I would suggest 1 part of prep mixture 2 parts dmso extra and three parts saline solution. That is plenty strong.

erin's avatar

Awesome! Will try it. But I am confused... which brand of hemoxycilin should I order? Any tips? Amazon has many options, I don't know who to go with. And some of them are extra expensive.

Bob's avatar

Then if ozone is not needed to oxidize, could heating the powder to 100C for a few minutes be used to sterilize for intravesical application? Also for rectal, what would be the dilution and quantity, and is there a retention time, or just leave it?

erin's avatar

My impression is that this is very much a work in progress, and it is now up to us to experiment at home and report back. I haven't done it yet but plan to.

Bob's avatar

Thanks. I meant to post directly to Doc G, but still learning to navigate Substack.

erin's avatar

Huh? Where is the info on how to get? And how to do at home?!

The article says it will talk about it and then doesn't.

I have been waiting so long for this.

-------'s avatar

Exactly. There is no mention of how/where to get it for use at home. A lot of suggestions in these comments, but I was wanting the info from the good doctor him/herself . . .

Aida's avatar

Hi Dr. where can I find the protocol for DMSO for chronic pain please.

NP or Bust's avatar

I have a BIG success story from my own life this past week. Combo of oral DMSO with 12mg tablet of ivermectin. It worked like a miracle. Seriously, unbelievable muscle pain relieved in 2 doses given, separated by 6 hours. BUT.. I smelled so bad my husband could not stand be be near me. Slept in another room for 2 days. Could not stand being with my smell in the car. 🦨 Someone, PLEASE, advise about DMSO odor. Thankfully, this happened over a long weekend, where my work as an RN and nurse practitioner student would be directly impacted. HELP!!!

🦨🦨🦨🦨🦨🦨

Mike H's avatar

This is the only place I have ever seen the odor problem addressed with a claim to be lower odor product. I don't know if it would truly be lower odor though. It is also one of the brands MWD recommends. It might be worth a try. Nothing to lose.

https://tinyurl.com/2s3duxej

Lance Grindle's avatar

There is only 'one hematoxylin'. In powder. Are you in a big hurry ? a patient is coming down here (Ecuador) next Sat. leaving following Saturday back to Tennessee. He would be willing to take back (He's taking other things) either Hematoxylin in powder or one mixed for you by myself (or both). Be happy to do that.

Rachel Stevens's avatar

Dear Dr. Grindle and MWD,

What is your experience / opinion on treating breast cancer with D-hematoxylin?

(I am F 46yo pre-menopause. Specifically my diagnosis / history is ER+ PR+ HER2- early stage DCIS in one side and a previous <1cm Stage I slow growing invasive tumor (IDC) in other side. Both areas were surgically removed via lumpectomy with clear margins - NO chemo, but 5 days of targeted radiation treatment on each side). NO tamoxifen or any other Rx’s taken. My hemo onc (and really whole care team) has tried to fearmonger and badger me into taking tamoxifen, but my research has shown that the absolute risk reduction is only about 2-3% with taking tamoxifen (while they only tout the 30-40% RELATIVE risk reduction for recurrence), so not worth the side effects and further Rx cascade to me.

If my cancer should recur, I am seeking alternative effective therapies, and am willing to travel for it. I want to be armed with a plan before being rushed into conventional treatment again in the future.

Any info or tips you have are appreciated!

God bless you immensely for your work and care!

Paul R's avatar

I am grateful, and incredibly impressed! by your dedication and time required to research these articles, write them, and publish them in a way that is cogent and available. I've been archiving these plus articles on ClO2 for easy reference.

Thank you.

A Midwestern Doctor's avatar

Thank you. I don't publish as often so I have the time to write detailed pieces like this.

Rusti's avatar

Something completely different.

A bit ago, I posted what is probably a wistful thought: that our host in uncovering the forgotten sides of medicine might help reconstructing medicine as a healing art as it was before the Flexner Report.

To that end, Kathleen McCook's substack From Ebla to E-Books: the Preservation and Annihilation of Memory <kathleenmccook@substack.com>

has a post:

Curious Cures: Medieval Recipes, April 11. There was medicine before Flexner. Who knows what is discoverable when healing becomes the objective.

Dr. McCook is a Librarian and scholar of library history and is particularly interested in the preservation of knowledge. Her interests range widely and just happens that this one deals with medicine.

Ed Eccleston's avatar

I wonder what it would take to get this to RFK?

sue's avatar
12 avr.Edited

Incredible. I'd bet if you created a fund (maybe in combination with something that already exists like Dr Kory's) to fund promising research on these alternative treatments, many of your readers would contribute.

Typos?

"The most common side-effect in Tucker’s patients was fevers in patients with large tumors (which subsided as the fever began to regress)" Do you mean as the cancer began to regress?

",,,because most of the changes D-hematoxylin creates directly destroy cancers rather encouraging them to transform back to normal cancers" Do you mean normal cells?

A Midwestern Doctor's avatar

Thanks fixed. My *hope* is that what me and Kory are doing will motivate the new HHS to study them.

Mouzer's avatar

I was thinking the same. I wonder if Dr. Kory's fund would be a place where one could contribute, given the trials are in another country. Maybe he should be approached.

Stan's avatar

Thank you so much!

Can you recommend sources for D-hematoxylin?

Also--when combining D-hematoxylin with DMSO for injection via catheter into the bladder, can RO water be used instead of saline?

A Midwestern Doctor's avatar

All the sources we use for hematoxylin are not for general consumers (rather for labs etc) and I did not have ability to vet the easily purchasable ones.

Glenn Swiatek's avatar

What would be the downside of mixing 100 or 150 mg of hematoxylin in perhaps 10 or 20 ml of DMSO and diluting that into a large glass of water, and drinking that once a week ?

Thank You, From Colorado

Stan's avatar

Okay. How about RO water in place of saline?

Lance Grindle's avatar

If by RO you mean reverse osmosis, yes should be compatible with the rest of the D-hematoxylin treatment. Only that it is not completely sterile. What are you thinking about administering the D-Htx for ?

Stan's avatar

Injecting D-Htx and DMSO into bladder as described in the article in hopes of dissolving scar tissue/fibrosis resulting from trans-urethral ultrasound ablation of the prostate for cancer followed by a couple of months of radiation for metastases in seminal vesicles and nearby lymph nodes. (Scar tissue obstructs urethra, can urinate some but need to use catheter to empty completely.)

Mouzer's avatar

I looked up Hematoxylin. There are different types. The protocol in this article discusses preparing it. D-hematoxylin is the name AMD created to discuss the compound for ease in the article, so it would not be commercially available pre-prepared. It is a very long article, but should be read thoroughly. This compound does not treat all cancers similarly, having excellent effects on some and minor on others, not only given the type of cancer but any treatments that are or were made before using it.

Lance Grindle's avatar

I am very curious about your comment about 'but any treatments that are or were

done before using it'. Would you care to elaborate on why you you mention that ?

Mouzer's avatar

You will find statements such as these throughout the article. I do not know if any one particular treatment will necessarily affect any one particular person for any one particular cancer type, but this treatment has limitations. And clearly, in some cases, people did quite well after and combined with conventional treatments.

"Younger patients with aggressive cancers generally responded better than older ones,as did those with minimal or no prior chemotherapy..."

"That project involved treating approximately 85 patients, with the cure rate in patients who had not previously received chemotherapy averaging between 80-90%. As such D-hematoxylin is an excellent cancer treatment but it is not perfect and will not work for everyone."

"On average D-hematoxylin treated 80-90% of the cases where it was used, a figure that resulted from certain scenarios having a much better response to D-hematoxylin. For example, in patients that who are fine three months post-treatment, virtually all have maintained an indefinite remission and there have been no relapses in all patients who’d never received chemotherapy prior to a (complete) course of D-hematoxylin.Note: patients who have received a full round of chemotherapy prior to D-hematoxylin tend to have the worst response to it."

Lance Grindle's avatar

Thank you. You are correct on the paragraphs. Brought to your text above. May I clarify and comment on each of the (4) paragraphs above?

On Hematoxylin itself Hematoxylin is only of one type and has only one formula. The different 'types' of hematoxylon refer to the different mordants added to Htx (abreviated) like Iron, aluminum etc. and that only refers to hematoxylon as a tissue stainer.

1.- Patients with previous complete chemotherapy we do not recommend doing D-Htx treatment. Patients without previous chemotherapy on the contrary do very well. Doing a significant amount of D-Htx treatment BEFORE chemotherapy does improve chemotherapy outcome significantly.

2) Younger patients, even with fast growing cancers do respond well with D-Htx although older patients are not at a significant desadvantage we have noted. The factor is "no chemotherapy" not "younger or older".

3) Without chemotherapy (and no vaccine interference) the indefinite remission is probably 80-90%. If all of the conditions specific to the individual patient are attended to.

4) I will stand by the statement that patient without chemo first and who has successfully finished D-Hx treatmente and is fine three months after that treatment - permanent remission is virtually 100%

Chemotherapy 'interferes with and damages' the mechanism of action of D-Htx. We do not know what that action is but it is for certain in the Dna.

Michelle's avatar

My 17 year old daughter is currently getting chemotherapy for alveolar rhabdomyosarcoma. I wish this were an option for her…

Stan's avatar

Do you include androgen deprivation therapy drugs in "chemotherapy"?

Lance Grindle's avatar

Actually no. I cannot affirm completely but I believe that androgen

deprivation does not mess up the positive action of Dmso-Hematoxylin.

We have many examples of chemotherapy interferring with D-Htx but no real examples of receiving androgen deprivation and then Dmso-Htx treatment. So I cannot be sure. If you have information to the contrary PLEASE inform me.

Sally's avatar

Do you have examples of Hydroxyuria interferring with D-Htx?

Steve Carpenter's avatar

Dr Grindle, I had stage 3 Non Hodgkins Lymphoma and went through 6 session of RCHOP chemo. I've been in remission with no further treatments for the past 2.5 years. If I had cancer again, would the chemo still negate the D-Htx? Or would it eventually start working again, as I've recovered?

Mouzer's avatar

Thanks for the clarification.

Lance Grindle's avatar

Steve. Thank you for contacting and for posing the question. I cannot state as a fact but I believe that the 25-year-distant chemotherapy would not negate the D-Htx. I can 'almost' affirm that, and thus should start working again. As we get closer to a better understanding of how this works our answers will also increase in precision.

Steve Carpenter's avatar

Thank you for responding Dr. Grindle. Just for clarity, it's been 2.5 years, but I understand the longer time from from chemo, the better it should work. I appreciate all you're doing, Dr. Grindle!

John Weaver's avatar

How can I find a doctor that uses alternatives like DMSO, CL02, etc. for breast cancer. We live in Texas but am willing to travel if needed.

James Miller's avatar

I think this may be your most powerful article to date.

Thank you!

A Midwestern Doctor's avatar

That's my hope! Lance is sometimes in FL. You two should connect

VictorDianne Watson's avatar

Thank you for your unwavering commitment to writing this series. I believe it will benefit many and know that it has benefited me and my family. It is unbelievable how much has been done to prevent these treatments from becoming mainstream. I pray that will all change with new leadership at HHS and all subsidiaries. Your long arm of readership has made it possible. It’s too late to put the genie back in the bottle! God bless you!

Arabella's avatar

This is rather off topic, but I wonder if DMSO, with or without the addition of this dye, could help treat impaired cranial capillary blood flow due to micro-strokes in the brain. I am just watching an astonishing presentation by the late Dr Andrew Moulden, who revealed that mini-strokes in babies, children and adults damage the cranial nerves that govern eye position and the corner of the mouth (among many other things), and that this can be clearly traced and precisely dated to having occurred after a vaccination event, by reviewing an individual's photos back in time. Here is the link. https://api.bitchute.com/video/diUhKm6YKvve/

A Midwestern Doctor's avatar

DMSO alone treats strokes. I went into that in part one.

Arabella's avatar

Would it penetrate into micro-capillaries? Apparently they are tiny.

A Midwestern Doctor's avatar

DMSO and treating zeta potential are the two best options I know for all of that.

jkes's avatar

Sir, would this be topical or orally administered?

STEPHEN j.PADUANO's avatar

Has anybody found a solution to the horrible smell DMSO has on the breath? Tried MSM not as effective as DMSO. In the last year I have used DMSO For many of the maladies an active 76 year old encounters IE. Cuts, bruises aches and pains etcetera. I used it on my scalp and ingested it orally and my dermatologist wants to know why my eczema is gone. I didn’t tell him. However, the most beneficial use for me is taking a teaspoon for my enlarged prostate it truly makes a difference. Problem is makes my breath smell horribly. Need suggestions my wife can't take my smelly breath

Lance Grindle's avatar

Give her a teaspoon every day as well. She will no longer 'smell' your breath nor her own.

The problem arises when you grandson comes in and smells 'two people' with bad breath

The solution is to give him a daily teaspoon of Dmso. He won't smell you both but will to his brothers and sisters.......... ad infinitum.....

STEPHEN j.PADUANO's avatar

I am going to try the Chlorella as suggested I am also going to try taking it with a dose of Chlorine Dioxide which I saw in a previous post. 1L of milk I can't do either and taking honey for taste isn't an issue. Let's all keep trying because it is obviously something to resolve.

The "ad infinitum" solution is great idea if my wife can get all of her fellow associates and employees to take it .. not

Christina's avatar

AMD has written before that drinking 1 L of milk a day is supposed to help. I can't seem to drink that much milk in a day. On the previous DMSO article, someone in the comment section referenced mixing it with honey, with a link to a research paper. I have a large family, and they all don't like the smell when I take it. They love me enough not to complain because they know that it helps me so much. It probably helps that its helped them with various burns, sprains, etc. Anyway, I tried the honey (7 parts DMSO, 3 parts water, and 1 part honey), and it seems to help significantly with the odor.

A Midwestern Doctor's avatar

That's to mitigate the taste of DMSO not to prevent the odor.

Christina's avatar

Ha, ha! thought it tasted worse… Hopefully my kids weren't lying when they said it smelled less.

Lance Grindle's avatar

I did not know that Christina ! Thank you for the information. I have not heard any other solution except for the other person taking Dmso also.

Mary's avatar

What purity DMSO are you using? Is it the pharma grade, 99.995%?

STEPHEN j.PADUANO's avatar

started with 90% worked down to 50% wife says no difference

Mary's avatar

What you are describing is the dilution. The question is what purity of DMSO you start with. The bottle I bought at a vet store was 99% pure, and it was quite stinky. The pharma grade I bought later was 99.995% pure, and it had very little smell.

STEPHEN j.PADUANO's avatar

Sorry i start with the 99.995% pharma grade and dilute down from there

Mary's avatar

Ok, we can rule out purity as the issue.

Rosie Langridge's avatar

Be grateful for details on how you use chlorella!

Sally's avatar

I use a 1/2 t. of powdered chlorella mixed with freshly juiced celery, cilantro & carrots = chelation therapy per Jon Barron.

Lance Grindle's avatar

You could look into dimethyl sulfone. As I remember this is the next step when Dmso is metabolized. Dr MWD please correct me if I am wrong..... I had some once. I think from Dr Jacob labs. comes in crystals, can take oral, is less potent than real dmso but has many of the properties as dmso. It does not produce the smell that dmso does.

STEPHEN j.PADUANO's avatar

MSM Solution from Jacob Labs,, problem is that it does not work as well for me. 8 ounces costs 30 dollars plus five dollars in shipping. It is in a Plastic container.. I recently bought 1 gallon of DMSO in a glass one gallon jug. The cost per 8 ounnces of the 99.995% concentration averages out to 8 dollars . I distribute it to friends and family .. I just tell them BYOB.. (Bring your own Bottle).

John Lawton's avatar

I have found that DMSO really helps with impaired urine flow so I assume it is having that effect on my prostate, although I have seen no experimental data to verify this.

STEPHEN j.PADUANO's avatar

For me Urine flow and urgency to go. I feel, yet I have not had it examined that the reason for the positive effects is that the DMSO is shrinking the prostate.

John Lawton's avatar

Indeed, I was long used to poor flow, but I developed sudden extreme urgency which made me take up DMSO to see if it could help, which it has done handsomely for both issues.

A Midwestern Doctor's avatar

A lot of people have found it helps BPH

Cason Gott's avatar

Hi, John....what exact formulation and method of DMSO are you using for your BPH??

John Lawton's avatar

I drink a teaspoon mixed into a small amount of reverse osmosis filtered water more or less daily. Sometimes I skip a day with no ill effects.

As I revile the taste of DMSO I follow the above with a chaser of cranberry juice.

Isaiah Antares's avatar

You are doing God's work, doc. Keep on rocking in the free world.

Don's avatar

This is an incredible report! Thank you so much.

NatureDoc's avatar

Is there any evidence that DMSO can treat HPV/genital warts?

A Midwestern Doctor's avatar

Some. The place where it gave the best results was when it was combined with another drug to prove an immune response. I discussed this in the first part of the cancer series, the skin article, and the infection article.

Lance Grindle's avatar

We have been having success for some years now in obtaining Acyclovir in PARENTERAL form (for i.v.....) (glass vial that receives a diluent) and re-consitituying

the medication. Mixing 40% this 60% Dmso and apply to the lesions for HERPES Zoster

infections. On the skin. Especially in the acute - few days - infections is very effective.

If months, helps but very little.

Lesions dry up quickly and, especially, seldom recure. In a few times used the same has

happened in genital. Infections; not have tried for G. warts. Probably less effective.....

Kimberly Greenlee's avatar

How do we make a contact with a Midwestern doctor by email?

LMS's avatar

You ever see a herxheimer from topical DMSO? I've used it twice, 1st time I just didn't feel good after, 2nd time I was kinda crippled up & stiff for 5 days. I am one of those super sensitive-weird responder to damn near anything. You are the only doc that seems to be aware of us hypersensitives.

Richard Bartholomew's avatar

Hi Dr. MWD,

You wrote that the mechanism of anti-cancer DMSO-Hematoxylin action is uncertain / unknown. I ran across this entry from a chemical supplier's website, and I wondered if you're already aware of this. Apparently, at least American Chemical Suppliers thinks that the anti-cancer mechanism of Hematein is already known:

"Hematein is an allosteric casein kinase II inhibitor with an IC50 of 0.74 μM. Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway and increases apoptosis in lung cancer cells. Group: Inhibitors. CAS No. 475-25-2. Molecular formula: C16H12O6. Mole weight: 300.26. Purity: 0.749. Catalog: ACM475252."

Alpha Chemistry is linked as a supplier.

Source: https://www.americanchemicalsuppliers.com/list/search?search=hematoxylin

Kathy Bassick's avatar

Hello, I’m wondering if you can give me a DMSO protocol for someone who suffered an ischemic stroke. My spouse. I have a bottle of 99% pure liquid DMSO +7030 Joe. Please help! I see anecdotal stories of people using it for a stroke, but nowhere does it mention dosages that I can find.

Holly Van's avatar

This may seem silly and trivial…but I have found taking DMSO in raw milk orally eliminated the smell that a person puts off when taking it. My husband had a stem cell transplant and since stem cells were stored in DMSO, he smelled so bad I couldn’t stand to get near him for a while. Later I learned about using it and just to take it in something that masked the taste I used raw milk. None of us ever developed the stink. I read Dr. Jacob’s book and he briefly mentioned the same outcome in the Chilean children and attributed it to them drinking raw milk. Hope that helps someone who is using it orally.

Jeff Prager's avatar

I have both Hematoxylin and DMSO but don't know what a subcutaneous mixture would be for humans. I can't afford to pay for Substack subscriptions but I paid for this one with the hope that someone, anyone, will help me learn to mix DMSO and Hematoxylin properly for cancer and subcutaneous injection. Someone, anyone, please help me. jprager@rocketmail.com

Sk4vrddw@protonmail.com's avatar

Did I miss something about topical use? How to mix the DMSO and hematoxilyn for topical use?

How does one find some one with the equipment to prepare the hematoxylin?

Incredible article and research but sadly this still feels somewhat out of reach to do at home.

I love the crowd sourcing idea!!

Nancy Barbic's avatar

Is it safe to use DSMO with a titanium hip replacement.

Em's avatar

Ms. Nancy, purely anecdotal. However, I use DMSO to address several chest/spine pain. My ribcage was surgically reconstructed and I have a titanium plate holding my sternum together.

I have not experienced any ill effects resulting from topical application of DMSO over a titanium inplant.

In fact, the effects are so significant enough that I am planning to begin oral treatment. My spine was broken during the initial surgery and the DMSO has allowed me to have greater freedom of movement in my leg. However, my progress has slowed causing me to try the more systemic benefit oral treatments may provide.

Nancy Barbic's avatar

Thank you for your response. It is greatly appreciated.

Sally's avatar

Dear Dr MWD & Dr Grindle,

My heart is filled with gratitude & hope because of your WONDERFUL research article, THANK YOU SO MUCH!! And a HUGE shout out to Health Ranger Mike Adams for directing me to this site a week ago via his podcast!

Personal hx: 59y F dx w/mpn blood ca 5 yrs ago, specifically et; d/c hydroxyuria 2 mos ago due to ^s/s, started Cl02; current platelets @1.6 mil & rising but minimal s/s; work FT as school RN.

Would you please direct me to a practitioner well-versed in administering D-Hem? boydsgalsal@gmail.com

Sincerely,

Sally

Rich's avatar

All the bio-chemical distributors I contacted don't sell to the public and require proof you are legit bio research lab before they accept your order.

Neal Sundberg's avatar

Thanks for doing the leg work. I ended up ordering something from Amazon: https://www.amazon.com/dp/B0CQNK6WT9

Was planning on using externally (squamous cell), as an alternative to surgery. But after receiving it, haven't used it yet. Not sure that I trust something like this coming from China.

Rich's avatar

I have received 3 shipments from them. shipped from NY. I have looked up the mfg website in China. It all looks legit to me. We have used it topically and orally with DMSO and seen effect. Sure seems like real Htx to me.

Dan Star's avatar

I use DMSOStore Roll On. I use a wood pole with a camera fixture to hold the Roll On bottle. Now I can cover my whole spine easily anytime. F Hospitals…they infect you then gaslight you.

Mike H's avatar

I thought I was the only person with a roll on bottle taped to a stick so I could reach my spine! Great minds think alike.

cstal222's avatar

A couple of times you have mentioned DMSO for Raynaud's phenomenon, but how is the DMSO applied? Is there a protocol?

J-R Salomon, PhD's avatar

Where does one get hematoxylin? Any advice? Thank you!

What about using Spirulina (with phycocyanins) instead of hematoxylin?

Mr ShufflesOG's avatar

Chlorine Dioxide for the odor. Details on usage anyone? Thanks!

Javi Escobar's avatar

Where can I buy topical DMSO for muscle and joint pain?

DUANE HAYES's avatar

The farm feed supply stores have it, like tractor supply and Big R, I use it for sore joints and muscles. By itself the DMSO stings but I apply another layer of "Blue-Emu" (Walmart), and that takes all the sting out.

Sherri's avatar

👏🤭👏👏🤗. I don't know if it was you but I know in reading the research on methylene blue and the bad wrap about it can't be used if you're on SSRI's or MAO's? As usual it's gaslighting the patient died because they irrigated an open incision with methylene blue to find veins/artery/nerves? And that person died because of the syndrome that you get with too much serotonin because they were on SSRI, however it was an isolated case and I would presume that is another medical error as pretty sure it was known to be cautious When using MB if you are an SSRI and with more invasive measures of using MBIV and/or in open wounds like that I would think it's just common sense but I totally could be wrong. But the point is that's pretty much the only documented proof that they have in that area???

Thank you for all that you do to bring information to us ❤️

❤️🙏❤️

Terry Steichen's avatar

Several questions bugging me from your (excellent) DMSO series:

1. How long does DMSO stay in the body?

2. How is it removed (if it is) from the body?

3. What is the effect (and how long) of DMSO on pills that are swallowed?

Terry Steichen's avatar

Well, I've been following your series and had not found answers (or would not have asked). I looked at the two linked-articles (above) and still don't find any clear answers.

The best I can guess is that DMSO's solvent action seems to be transient. So, in general, if you wait a couple of hours after taking (oral) DMSO, you don't need to be concerned about the danger of it boosting the effect of subsequent medication you may take (particularly, I'd guess, if the medication is in the form of pills).

Is that reasonable?

Lance Grindle's avatar

Half life is documented at 48 hours. Eliminated as Dymethylsolfone, a change in the molecule and is from lung, kidney and skin principally. Pills are generally not affected by Dmso.

Rich's avatar

So we should mix fresh D-hemotoxylin every day for best results? Or how long does a batch remain viable?

Thank you

Lance Grindle's avatar

No. Not need to mix daily. A mixed batch is good for several weeks. At least.

Stuart Hutt's avatar

If our "Health Care" practitioners were competent in DMSO and chlorine dioxide we would be healthier but Pharma would be out of business.

bittersall's avatar

Thank you so much for this information. An amazing contribution to your readers. I would make one comment on the use of DMSO....I was taking it orally at one time to increase the benefit of Chlorine Dioxide. After a while, my wife asked me "Why do you stink so lately?" Don't know if it has that unfortunate effect in all situations..........

Mike H's avatar

I have been using dmso for years on my wrist, knees, and back. Its a miracle. You don't even have to swallow it for it to make you smell like garlic. It goes through the skin quick, and into the body, and your body will produce the smell. An unfortunate side effect of a great medical tool.

Alex Audette's avatar

Dear AMD,

Just read your great post on DMSO-Hematoxylin combination and it brought to mind a problem that I have been considering for a while regarding methylene blue administration. As you probably know, one of the chief emergency indications for MB is for methemoglobinemia and possibly heparin neutralization (in addition to it's many other uses). However it is also being extensively used in the anti-aging, and longevity spaces in Europe as well. I am now the science officer for a nutraceutical company that uses it in this capacity (previously I was an integrative TCM clinician) and I have always been somewhat worried about what can happen when an interstitial infiltration occurs with MB (following case:

Dumbarton TC, Gorman SK, Minor S, Loubani O, White F, Green R. Local cutaneous necrosis secondary to a prolonged peripheral infusion of methylene blue in vasodilatory shock. Ann Pharmacother. 2012 Mar;46(3):e6. doi: 10.1345/aph.1Q560. Epub 2012 Feb 28. PMID: 22388329.)

While this is an example of a prolonged administration in the ICU which was probably left unsupervised which led to the infiltration becoming worse, it would generally not happen in the anti-aging space due to continuous monitoring of the 20-30min infusion of 50mg that usually happens. However, in the event that it did happen in this space, it occurred to me that both promptly stopping the IV MB, and applying DMSO topically both locally and distally to the infiltration site would help to disperse it into the circulation and lower the chances of the severe consequences mentioned in the paper above. I would love to hear your thoughts on this matter as it is better to be prepared for this eventuality should it occur so that it can be promptly be dealt with.

A Midwestern Doctor's avatar

I do not know enough about MB to tell you

Alex Audette's avatar

Ah well. Thanks anyway. If you know of anyone who is well versed in it's admin, I'd appreciate if you could pass the question along...Be well.

pimaCanyon's avatar

what dose was the person using who went into vasodilatory shock?

people taking MB for improved mitochondrial function, improved endurance, improved cognitive function, etc. are taking doses of 3 mg up to maybe 10mg, often intermittently, say a few days on, then a few days off. Are these low doses likely to cause something like vasodilatory shock?

Alex Audette's avatar

I’m not aware of any cases where vasodilatory shock was caused by MB. It is generally a treatment for it at a dose of 1-2mg/kg IV given over the course of 20min either preoperatively, during an operation or postoperative. Oral dosing with low doses like 3-10mg is very safe and won’t cause any issues. To increase MB effectiveness at this dose, I usually add 1tsp of 100% DMSO in a glass of diluted juice aling with about 8mg MB. Several days on, several off with no issues.

Rusti's avatar

Thank you!

You use the term "leukemias" as a generic...I think it must be a taxonomic usage: cancers of a type. I infer: blood marrow cancers? If I have that right... Does that usage include MGUS/Multiple Myeloma?

Lance Grindle's avatar

In the elaboration (in the substack) of the parts of text that corresponded to me - such as

all of the images 'Bone Marrow Neoplasia'- I was the one not MWD who used Leukemia.

Your point is well taken. Regarding treatment MGUS or Multiple Myeloma both seem to

and should be susceptible to improvement with use of D-Hematoxylin.

Rusti's avatar

Dr. Grindle, perhaps I was not clear enough. The word Leukemia is used..which I took to mean the disease Leukemia. Then there are uses of the term "leukemias," which I took to mean a taxonomic observation. That is, grouping a set of cancers that share a common trait. But maybe not which is what my question was aiming at: are MGUS/Multiple Myeloma "leukemias" in the sense I thought was being described. If so, then treatment options discussed with the leukemias would apply to MGUS/Myltiple Myeloma.

Or maybe not. There are so many types of cancers and everyone who has to deal with cancer has to sort through all sorts of possibilities. Particularly in the alt- world.

Then there is this:

•DMSO treats many challenging complications of cancer such as cancer pain and amyloidosis from multiple myeloma.

Aha! Now that sounds very interesting and worth hunting for.

Thank you for your research. If it works out, maybe I mosey down to Quito. I was there some years ago. Quite a place.

Best regards

Andi's avatar

AMD, have you ever seen DMSO used to treat paraneoplastic syndrome? Or think it could be useful? My friend has this rare condition and if DMSO can help I’d appreciate guidance. Thank you. 🙏

A Midwestern Doctor's avatar

Have not. While there is a lot of research on DMSO, there are so many things out there, many of them still have not been tested and I didn't know anyone in practice who used DMSO for this.

Andi's avatar

I appreciate your kind and prompt response. And of course, all of your brilliant articles in DMSO and other topics. You’ve become one of my staples for learning more about the future of healing.

Lance Grindle's avatar

I have also not used D-Hematoxylin for paraneoplastic syndrome. I would very much up for trying it especially in a very severe and/or frequent situation. If the damage is in the

Dna (which it likely is) then there is a good chance of relief. Again, as I have mentioned several places here- thanks to the low low toxicity of D-Htx there would be little downside to trying it. The main inconvenience is only i.v. s are tedious and boring to do. Having someone available to do it competently would help immensely with that. It might be worth it to try for two or three weeks - it could save a lot of suffering. What I will say here is that if it is successful I would predict that the syndrome will never return. That is the case with essentially all of the cancers that are treated with D-Htx.

I would be very interested in helpinh out and in trying this concept.

Dr Grindle

Andi's avatar

Thank you so much. My friend is in a severe situation. If you would be so kind as to guide on the proper dosage and frequency, it would be so helpful. Is IV administration the best case for this, in your opinion? You’ve mentioned a couple of drawbacks. Could oral dosing be effective? She experienced breast cancer and then onset of the symptoms of paraneoplastic syndrome. The western medicine model has no answers for her. I’ve read nearly all of AMD’s articles on DMSO. I’ve mixed eye drops for a friend with macular degeneration, and I use the drops myself, just for general eye health. So I’m intrigued with this compound and its capabilities. As you mentioned, there’s really no downside. I appreciate any thoughts you have on dosing. I’ll keep you informed if my friends accept this wild idea of mine. 😌

Lance Grindle's avatar

Then keep this as reference for communication at some later time.

dmso.ozone.me@gmail.com Lance Grindle

Sally's avatar

Dr. Grindle, this email address is different (by one letter) than the one you communicated to Dave on the same date, please confirm which is correct?

Lance Grindle's avatar

You are correct. 'me' should be 'md' I apologize

karen k's avatar

Would DMSO help myelodysplasia. specifically RA MDS?

It is a 72 year man otherwise in good health who has made many lifestyle changes since diagnosis. Now has hemoglobin of 70. Apparently not eligible for stem cell transplant because of age.

A Midwestern Doctor's avatar

Possibly as it helps a few similar things but there's no data, so I can't say with certainty.

Lance Grindle's avatar

Karen, the treatment has a high likelyhood of 'working'. For varios reasons.

You could contact if you like. Dr Grindle

A Midwestern Doctor's avatar

Thank you. I really want this information out there.

Mary Fisher's avatar

Wow. Just wow. You are amazing.

A Midwestern Doctor's avatar

Thanks. This one was a lot of work (and part of why I was posting revisions of older article recently)

Mary Fisher's avatar

I’ll say! I was reading and reading and reading and then I looked at the clock and scrolled to see how much more there was - and scrolled, scrolled and scrolled some more! Very impressive as well as fascinating! And it’s news to me as well. Thanks for chasing this down!

Go west's avatar

I concur; AMD substack notices of new publications make my day as well as commentaries.

Joanne's avatar

Does your reference to the effectiveness of D-hematoxylin with leukaemia apply also to multiple myeloma and if so what protocol would you suggest?

A Midwestern Doctor's avatar

To the best of my knowledge no one has tried it for that. I could see why it would be helpful, but that's a guess rather than something there's any data to go off of.

Joanne's avatar

How do you find a practitioner?

Lance Grindle's avatar

Hello Joanne, "speaking theoretically" - there is an article below that was done as 'in silicio' that gave hematoxylin the best match of a large list of candidates for a docking site on Dna. Search term that probably would give it is" Hematoxylin binds to mutant Calreticulin and disrupts....' or Blood 8 April 2021 Volume 137 Number 14.

Personal experience (ours) with exactly the D-hematoxylin of this, Dr MWD's, substack produced interesting reductions in the affected proteins in circulating blood in a patient that unfortunately abandoned her treatment early, for reasons other than medical.

I am in agreement with MWDs thinking that it could/would be helpful.

I see very little downside in trying it given D-Htx's negligable toxicity.

Jacob99's avatar

20 years ago I had a small cell carcinoma of parodic gland. They did surgery chemo and radiation. I had a support of wonderful functional doctor. So far, I'm OK. If G-d forbid, this happens today. What would be a proper treatment? Skip all conventional treatment or somehow mix two approaches?

A Midwestern Doctor's avatar

It's really case dependent, so the ideal answer is to work with an integrative doctor who has familiarity with cancer.

The main issue you want to avoid is waiting too long to use conventional therapies for an aggressive and fast growing cancer.

sue's avatar

Of course you don't want to wait a really long time, but this exact argument is used by many oncologists inappropriately to push people into chemo before they have a chance to do research. They say it's pretty rare that you don't have a couple months. Since surgery and other alternative treatments can cause metastasis, I think most people would be better off doing certain alternative treatments and taking certain supplements to reduce that risk for 6 weeks before traditional treatment. That's what I did with an aggressive tumor and in the process the tumor shrank. And 3 years NED so it appears to have not metastasized.

I've told many people about supplements they should be taking before surgery (based on research), but that's not being reported by many sources unfortunately.

Mouzer's avatar

I had a different cancer, but I struggle with the same question. I knew of alternative approaches at the time (almost 10 years) but they didn't have the kind of detailed information now appearing here and from other doctors.

I think the thing to do is take steps to ensure it doesn't come back. To that end, I have made a lot of changes, including changing doctors. Today I might mix two, but as I get more information, that keeps changing.

Wanderer's avatar

Hi! I was hoping to get some input into a situation I have with a family member. This is her third time getting breast cancer (this last time it is stage 4) with metastasis to her hip.

She’s undergone everything under the sun, even as far as going to Switzerland to get treatments that are not approved in the US. She underwent heating/sweating treatments, etc

that DID reduce the size of her breast lump, and then she had it surgically removed. The second time it came back she underwent chemotherapy.

This time she just started radiation to her hip and neck/breast lymph nodes. The oncologists are telling her that there is no evidence that radiation can prolong her life, but are still recommending her to do it. They have had her on Verzenio for the last 9 months (which after a while stops being effective). She will stop the Verzenio during the radiation treatments (which she is undergoing now and last till November) and then will continue it again.

I have told her about DMSO and she is willing to try it. Currently, she’s using it topically prior to radiation treatments (25% strength), though it ends up being longer than 20 minutes between the application of DMSO and the actual radiation treatments.

It seems that the Verzenio is starting to lose its effectiveness in her, so I was hoping that the DMSO might increase its effectiveness, but am not certain as to what dose to advise to her. Just topical? A gram orally daily? I’m just not sure. Plus, it’s unclear what the DMSO might do, whether it could increase the toxicity of the drug (however I’m leaning toward it being protective of the potential adverse effects of Verzenio, specifically inflammation of the lung and blood clots). I am almost positive that sharing her addition of DMSO to the oncologists would provoke unaccountable levels of horror, which is unfortunate because if she needed to reduce her Verzenio dose due to increased toxicity we wouldn’t be able to share that either.

Any tips or ideas would be most appreciated.

Also, for the D-hematoxylin mixture… i

I was wondering if it would be worth it to try that as well, though the only thing going for her in that respect is that she is unvaccinated. It seems that mixture doesn’t do as well with solid tumors, plus she’s already had chemotherapy. This would be a Hail Mary for her. Everything else has failed and modern medicine is hardly helpful.

Thank you so much for your time.

Sherry's avatar

Can dmso and hematoxylin be used orally and topically at the same time or would that be too much?

ALIRO VALDES's avatar

Hematoxyline is very difficult to buy. Only laboratories can. Giving some alternative sourcing would be very helpful.

I did not succeed until now.

Brad Lindblad's avatar

Various types of soft tissue sarcomas are indicated in the work. Epetheliod sarcoma is a rare one that I currently have again after 13 years. The initial tumor site is right below the skin on the palm. Would a topical application be good here?

Diana's avatar

I'm so grateful for this incredible work which I believe will save many lives. Thank you!

KML's avatar

Is DMSO effective in dissolving Giant Cell Tumors (benign)?

Natalie Myrick's avatar

I would like to know how my daughter who is battling stage 4 breast cancer could use DMSO? Can she take it orally? If so, how much? She's currently on Makis' protocol alongside chemo and immunotherapy.

A Midwestern Doctor's avatar

1) D-hematoxylin tends to not work as well if someone's already done chemo.

2) DMSO and ivermectin works best topically for localized tumors where you can put it above it.

3) DMSO alone can mitigate her side effects, but there may be a potential chemotherapy potentiation issue (which could be good or bad) so it would be best to take it apart from it.

What exact Ivermectin/FenBen/supplements protocol is she doing?

Natalie Myrick's avatar

Oh, and the supplements are CBD oil, vitamin D3, berberine, turkey tail, black seed oil, curcumin, and sadly I can't remember the rest

Natalie Myrick's avatar

She's using Makis' protocol that includes Ivermectin at 90mg daily, and fenbendazole at 1500mg. daily. She's still getting chemo and immunotherapy too.

Natalie Myrick's avatar

She just got updated scans yesterday but won't know the results until her appointment on Monday. She's had to get a few blood transfusions because her hemoglobin has been low, I'm guessing due to chemo. But she is back to work. She was diagnosed when she was 38 weeks pregnant & Her son just turned 4 months old.

Deb Siddle's avatar

I’ve read the hematoxylin is toxic . How can we use it to treat cancer but not poisonous us?

Bob's avatar

Any thoughts on this hematoxylin? Product of Mexico. Says "Pharmaceutical grade"

https://aurorasilk.com/wp/product/logwood-extract/

phil@terryism.com's avatar

If I wanted to improve my use of fenbendazole would dissolving the contents of the capsules into DMSO and then diluting in a glass of water improve bioavailability of the fenbendazole. I have 444mg pure fenbendazole powder in capsules and Nature's Gift 70/30 DMSO/Distilled water.

A Midwestern Doctor's avatar

I know people have had success doing that with ivermectin but I do not know of anyone who's tried it with fenben so I don't have any data to go off of.

phil@terryism.com's avatar

I'm a colorectal cancer patient taking fenbendazole which has poor bio-availability. Would dissolving the fenbendazole (888mg) powder from the opened capsules in a teaspoon of 70/30 (Nature's Gift pure DMSO/Distilled water) and then adding that to a glass of water and drinking be a good way to improve fenbendazole bioavailability?

phil@terryism.com's avatar

I'm a colorectal cancer patient taking fenbendazole which has poor bio-availability. Would dissolving the fenbendazole (888mg) powder from the opened capsules in a teaspoon of 70/30 (Nature's Gift pure DMSO/Distilled water) and then adding that to a glass of water and drinking be a good way to improve fenbendazole bioavailability?

phil@terryism.com's avatar

I'm a colorectal cancer patient taking fenbendazole which has poor bio-availability. Would dissolving the fenbendazole (888mg) powder from the opened capsules in a teaspoon of 70/30 (Nature's Gift pure DMSO/Distilled water) and then adding that to a glass of water and drinking be a good way to improve fenbendazole bioavailability?

Tony Earhart's avatar

I bought a bottle of hematoxylin and ready to use it with DMSO. What are the mixing protocol for taken orally

CCoats's avatar

Just wondering if anyone knows of any US doctors that would possibly be willing to give this type of treatment to someone with AML, that has recently been diagnosed and has already had 2 rounds with breast cancer in the past.

John Morauski's avatar

Greetings. I have an urgent clarification from the dosing segment of this paper. One part indicates 1.5 g of Hematoxylin to 12 ml of DMSO, which is 10 g in 80 ml of DMSO. However, further on, it states, "Note: all the above protocols by Dr. Tucker reference a D-hematoxylin combination of 25 grams of hematoxylin in an 80mL container of DMSO (which typically Tucker gave 2mL of each day)." I need to clarify this as soon as possible. Thank you.

Candy Jo Simpson's avatar

Could I dilute the 99% DMSO with a carrier oil such as Castor oil SAY 4oz CO to how many drops of DMSO for topical use ?

Lloyd Chambers's avatar

Can DMSO be used concurrently with a blood thinner?

Lance Grindle's avatar

Not every day. That would be extremely tedious and time consuming.

The reality is that Dmso-Hematoxylin seems to get better and better with time, like a good wine.

Reality is that we have used after several even many months.

Lance Grindle's avatar

Rajiv. I have the impression that you belong to IAOH. Do you, or am I mistaken.

Book - Dmso Handbook. Has a green frog on the cover published in Germany.

Rich's avatar

Any recommendations on storing mixed D-hemotoxylin? How long is a mixed batch still safe and effective to administer?

Thanks

Sk4vrddw@protonmail.com's avatar

I'm curious if anyone has pursued this therapy and if so how you went about it. I was hoping this would be just simply mixing some powder into the DMSO and applying but its more complicated than that. Just interested in hearing anyone's experience with pursuing this therapy.

RCON's avatar

Important question: I am currently trying to kill CSC’s leftover post op of a tumor. I have had success without chemo, radiation or anything else besides the numerous and varied repurposed drugs and treatments, including methylene blue combined with infrared/red light (photodynamic therapy). Obviously MB is a dye like D-hematoxylin..Does MB have the same benefit (research says there is some benefit from the combined therapy.) but where can I purchase D-hematoxylin from a trusted source to use with the DMSO I use with MMS-1 topically on my skin (which seems to be working) Thanks for any guidance.

Jenny Taylor's avatar

Hi can I purchase DMSO in the UK?

RebeccaStar's avatar

Dear Doctor

A friend of mine who had breast cancer has been drinking DMSO in the prescribed doses, then she read on google that it doubles the effect of alcohol if you drink it while taking DMSO. Is this true?

A Midwestern Doctor's avatar

The only reference I was ever able to find for this came from the guidelines Merck sent out to their investigators in 1965 (which can be found in Pat McGrady's book DMSO the persecuted drug).

"Some patients have noted an apparent potentiation of sedatives like barbiturates or alcohol. These findings have not been observed in the laboratory."

"alcohol—In laboratory animals, DMSO, given beforehand, reduced deaths from lethal doses of alcohol; but DMSO increased the mortality when given after alcohol had taken effect. A pony of cognac will reduce the smell of DMSO."

Based on this, my best guess is that it slows their liver metabolism a bit, but may also enhance CNS penetration.

RebeccaStar's avatar

Can DMSO help my cat who I think has diabetes?

RebeccaStar's avatar

Below is a statement from you in this thread so I’m confused.

A Midwestern Doctor

AUTHOR • Apr 13

The main drugs DMSO had been identifed to potentiate were benzodiazepines and alcohol. When DMSO is applied topically in a region, there is a relatively small risk for a potentiation effect. Also in the DMSO bicarbonate studies, the patients were on IV DMSO and opiods and did not have issues (rather they stopped needing the opioids).

LIKE (3) • 6 REPLY

A Midwestern Doctor's avatar

No one has reported any issues with that, but I would advise not taking and then drinking significant amounts of alcohol afterwards.

RebeccaStar's avatar

Are you speaking of the post on your thread about the issues with DMSO being a byproduct of the paper industry & pine bark causing central nervous system damage with strokes, epilepsy etc. I didn’t see any answers I led this is what you are referring to. That post was from another doctor warning it’s not safe. Please advise.

Thank you!

RebeccaStar's avatar

Ok thanks. I guess you saw that posts?

A Midwestern Doctor's avatar

I just looked through the article in a bit more detail.

The pine bark supplement she put a link to there (after arguing it was much safer and effective than DMSO) had an affiliate sales link (meaning she gets a cut of each pill that's bought). The purpose of that post was to scare people so she could make money and that explains why she was so resistant to looking at the truth behind any of it.

A Midwestern Doctor's avatar

Someone just sent it to me. She does not at all know what she's talking about (e.g., at the very start she said EDTA is formaldehyde which is akin to saying Texas is Antarctica) and her points on DMSO displayed give or take no understanding of the subject.

RebeccaStar's avatar

What is CNS? I take clonazapam & have couple glasses of wine. I just started using DMSO on my thumb joints. A miracle! No pain. Then I read here the post that it’s a toxin from the chemicals used by paper mills & pine bark. Can cause central nervous system damage. WTF??? HELP!!!

RebeccaStar's avatar

I used DMSO on my arthritic thumb joints & it worked. Amazing. Then after 3 days I needed to use it again but it didn’t work so good second time. What would be the reason? How often can I put it on in a day? I’m stumped 🤔

Rich's avatar

Add borax, sodium borate. Literally a pinch (1/16 tsp) in warm water once per day. I prefer MSM to DMSO for muscle joint pain relief. They are almost identical molecule.

RebeccaStar's avatar

All I see is it’s for laundry & cleaning.

Rich's avatar

Look deeper. It is forbidden in Germany for a reason. Walter Last wrote a long article about borax, and there is another big article too, don't know the author. These go back 25-30 years. Also American doctor Jorge Flechas has a youtube video lecture about it.

Elizabeth Krispin's avatar

Can anyone share a link of the full RFK Junior hearing today?

Mark Gerber's avatar

Is there any documentation for using DSMO to treat chronic kidney disease (CKD)?

Thank you.

CK's avatar

Does anyone have any experience with using DMSO along with CBD oil? Is there any advantage to combining the two, or any harms?

jkes's avatar

Wonderful. What application/route would be recommended for down syndrome?

Mark Gerber's avatar

Is there an update to Dr. Walker's 1993 book listing the members of the American College of Advancement in Medicine (ACAM) Physicians--United States.

Interested in members in South Carolina and northern California.

Also, has Dr. MWD written on the issues of mold? Thanks,

Mark Gerber

EA's avatar

Thank you A Midwestern Doctor for researching and publishing this information. My wife has recurrent metastatic leiomyosarcoma with no good treatment options. Now thanks to your efforts we have hope since connecting with Dr Grindle. May God bless you both for bringing this option to the world.

Danbob's avatar

I'll definitely consider this. Everything I do online is anonymous for obvious reasons. How can I get the work in front of you?

Pam's avatar

Waiting on my DMSO order-for tinnitus-but now the side of my tongue with a 50 year sublingual variscosity has quadrupled in size so much I cannot eat, talk or swallow without deliberation. The emergency room sent me home with steroids and instructions to f/u with ENT. My DMSO arrives tonight. Planning on drinking it diluted. (I will do the skin test first).

Apparently, no one has ever seen anything like it. ER Doc said mangianoma-will need surgery. CT Scan w contrast came back clear for tumors. I did find a medical journal describing the same issue I have saying it is the only one on record. Great! I am on my own and only have hope because of this article. Thank you MWD

ANY TIPS-pam.roland@raveis.com

Roxanne's avatar

Thank you, Dr. Grindle, for being willing to collaborate with our AMD.

Robin Anders's avatar

Absolutely incredible. What a resource. Thank you n

Kevin Purtell's avatar

Dr, a dear 78 year old friend of mine has had an incredible number of skin cancer surgeries on his face. He goes in every 6 months and every single time they find more to carve out. He was told this week that they will likely have to remove his entire ear lobe. I have been talking to him about DMSO. He is extremely interested in trying something non traditional. Can you point me in any particular direction to help him please?

Colin Driscoll's avatar

Have you put a post together listing all DMSO articles, with short summary, so one knows where to start, or share a specific post for an ailment with another?

I have a friend with an issue covered in the topic, but don't know where to point them, and while all of it is interesting (I've gone through them all), just can't recommend someone spend 30+hrs of their time.

I'd get them their specific info & then recommend further reading on their part, once their initial issue resolves.

Aida's avatar

How can I find a treatment for chronic pain with DMSO or a clinic

BlueHorse's avatar

Galleri - this is a new blood test that will detect 50 types of cancer (supposedly) whether they are just starting, or any other stage - by reading DNA. Friends are getting this test next week. What are your thoughts on this? I'm all for your research and trust what you say about medicines and cures. Thanks.

Danbob's avatar

I recently found an early stage colon cancer with this. I had a suspicion in a patient with transient rectal bleeding. I ordered a Cologuard, which was negative. I couldn't shake my suspicion, so I ordered the Galleri, and sure enough, it was positive. Had we let it ride with the CG, this would've advanced. Instead, we've been able to hit this thing hard, and he'll be spared surgery. I highly recommend as it catches serious cancers that often run asymptomatic until stage IV.

Burt Walker's avatar

I’d love to know if DMSO would help reduce inflammation after radiation treatment for prostate cancer. I’d appreciate it if anyone could share any knowledge about this.

Danbob's avatar

Yes. See my post above about topical application. With prostate, can use with or without Ivermectin. Its a good idea to remove the hair on the perineum and let things air out. Might start with 50% and work your way up. If using with IVM, wash off after 30-60 mins.

External Access's avatar

Hello to all... I am new to this forum as of today. I really hope the group will help me.

I have pancreatic cancer and was a light stage #1 before surgery. Sadly, I had the standard protocols of 8 rounds of chemo before surgery and only 3/6 after since I called it off due to concerns my oncologist was unreliable. and unneccessarily pushing more chemo.

Currently, I am blessed that after nine-months post-surgery my tumor markers have been very low( below normal) until this past month. At the time I had a bad bike accident and broke 4 ribs and the pain was incredible. Just prior to the accident (run off the road by a car) the markers were fine.

Currently the markers are just a bit higher than normal and I am told by my Functional Medicine doctor that a recuring tumor has not likely happened. A CT scan two weeks ago showed nothing and also confirmed that my lymph nodes were normal as well. So far....

My concern for the moment is getting the tumor markers back down and my (good) doctor has me on 100g vitamin C infusions and Thymosin Alpha peptite along with other supplements.

So my question is: despite the chemo and nine months post-op will DMSO or D-hymatoxilin work to kill the individual cancer cells before they multiply to the point that a tumor can restart?

If the doctors in this group and the other knowledgable menbers would please offer guidance it would be a big help. If a private message would be OK please contact me at live-on-scene@gmx.com Thanks to all.. Brett

Danbob's avatar

Perhaps DMSO alone as the D-HTX may not work as well after chemo, but DMSO alone has remarkable anticancer properties.

Wendel's avatar

I have a question about DSMO with regards to ocular implants for cataracts. If you have those in your eyes, can DMSO do damage to them? I broke my wrist and would like to use DMSO to help with healing but am concerned that I”ll end up damaging my eyes.

Stacey Mileti's avatar

My daughter has Stage IV colon cancer. Will you please clarify the type of cancer Joe Floyd had? It is described as "advanced metastatic colon cancer (e.g., in the lymph nodes and liver) with a poor prognosis (particularly since it was a rare lymphosarcoma)." Was it Stage IV colorectal adenocarcinoma or another type of cancer?

Elke's avatar

Hi MWD,

I don’t know how else to reach you, but I was wondering if DMSO is safe to use for varicose veins during pregnancy?

Noni Bird's avatar

I hope you are well Dr. and thank you for all your wonderful information. I was reading Dr. Love’s sub stack and I read this negative information on DMSO and wanted to know what you can say about this information she writes. I must inform my audience that DMSO is a byproduct of the paper mill industry. Poisonous chemicals are used to strip pine bark from pine trees. The toxic byproduct is sold for health supplementation.

DMSO may provide limited nutritional benefits to cells simply because pine bark is highly medicinal. However, it also has well-documented toxic side effects from the chemicals used by the paper mills that we should not ignore.

DMSO increases ROS production, decreases cell viability, and induces mitochondrial dysfunction through impairing glutamate transporter synthesis. Overuse causes traumatic brain injury, epilepsy, and neurodegeneration.

The screenshot below is from a study entitled Dimethyl Sulfoxide Damages Mitochondrial Integrity and Membrane Potential in Cultured Astrocytes.

Glutamate, the major excitatory amino acid neurotransmitter in the brain, can become potentially toxic when it over-accumulates in the synaptic space 42. As mentioned earlier, astrocytes are responsible for maintaining brain glutamate homeostasis via glutamate transporters 24. Oxidative stress inhibits glutamate transporter expression and function, which has been implicated as a main pathogenesis for glutamate excitotoxicity in a variety of pathological conditions, including brain ischemia [43], [44], traumatic brain injury [45], epilepsy [46] and neurodegeneration [47], [48]. The present results have demonstrated that DMSO causes down-regulation of GLT1 and GLAST in cultured astrocytes. In addition to increased ROS production, decreased cell viability and mitochondrial dysfunction may impair glutamate transporter synthesis by astrocytes. High concentration of DMSO has been shown to degrade membrane structure and disturb secondary protein structures within membrane proteins [26], [27]. This may also contribute to decreased expression of GTL1 and GLAST. Down-regulation of glutamate transporters may lead to neuronal excitotoxicity, thus exacerbating DMSO-induced neuronal damage. The results help to explain the occurrence of epilepsy in humans [14]-[18] and rats [49] following exposure to high concentration of

DMSO.

As you can see, DMSO is a neurotoxin. Neurotoxicants are many chemicals or substances that interfere with normal function and/or compromise adaptation in the central and/or peripheral nervous system. DMSO is associated with various central nervous system side effects, such as epileptic seizures, stroke, transient global amnesia, and more. Studies have shown that DMSO can produce widespread apoptosis in the developing central nervous system. If somebody is poisoned with COVID-19 technology or shedding, DMSO is a wrong and potentially dangerous treatment.

Thank you so much and I look forward to your response

Sincerely

Nora

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A Midwestern Doctor's avatar

Sorry just saw this.

1) Pine bark oil has a much higher toxicity than DMSO (going off LD50).

2) DMSO is not made from pine bark. It was a byproduct of a wood pulping process, but once they realized DMSO had medical properties, they switched to a completely differenty synthesis process to have a higher purity.

3) The article she wrote included an affiliate link to sell her pine bark oil. So she used a fairly classic internet marketing strategy: drum up fear, present a better product, entice people to buy it so she gets $. After talking to her for a bit, I realized she was not willing to change her position at all because doing so would cost her money.

4) The benefits from pine oil are completely different (and much less) than what is seen with DMSO.

5) The studies that show DMSO harms cells are holding them in DMSO at high concenrations for prolonged periods which will never be seen in the body, and at which most substances are highly neurotoxic. In give or take all the studies I've looked at, DMSO is at least 100 times less toxic to cells (by concentrations) than most commonly used supplements or drugs. For example, some studies show DMSO harms mitochondria if they are kept in 1-5% DMSO for 48 hours, but to have that concentration within the body, you would need to drink a liter per day of it, which is at least 100x what people ever consume.

RebeccaStar's avatar

Any answers yet??? I questioned the previous article about this but don’t see any answers from AMD.

Eric Silverman's avatar

Does anyone know if there’s any sort of database that shows physicians who use DMSO? I have had no luck whatsoever finding anyone in the northern NJ area. Thank you

lrfloyd's avatar

Dr. Love has a very different opinion about DMSO. It is confusing!

Dr. Ariyana Love - https://drloveariyana.substack.com/about & - https://drloveariyana.substack.com/archive

&

WARNING! Methylene Blue Activates Graphene Oxide! EDTA Preserves Spike Protein Production! - https://drloveariyana.substack.com/p/warning-methylene-blue-activates

....DMSO

Amandha Dawn Vollmer, Doctor of Naturopathic Medicine, has written about the toxicity of serotonin, known as serotonin syndrome, which results from using Methylene Blue. She also writes about liver and kidney damage risks, infertility, and more.

While I disagree with Vollmer’s promotion of DMSO, she writes an in-depth and comprehensive article on the harms of methylene blue.

Vollmer points out that “methylene blue hijacks natural electron flow in the body, especially in the mitochondria.” Disruption of your cell signaling functions interferes with every bodily function.

Methylene blue induces a Reactive Oxygen Species (ROS) from overwhelming toxic poisoning that leads to Mitochondrial damage. ROS results in adverse reactions from immune system failure.

I must inform my audience that DMSO is a byproduct of the paper mill industry. Poisonous chemicals are used to strip pine bark from pine trees. The toxic byproduct is sold for health supplementation.

DMSO may provide limited nutritional benefits to cells simply because pine bark is highly medicinal. However, it also has well-documented toxic side effects from the chemicals used by the paper mills that we should not ignore.

DMSO increases ROS production, decreases cell viability, and induces mitochondrial dysfunction through impairing glutamate transporter synthesis. Overuse causes traumatic brain injury, epilepsy, and neurodegeneration.

The screenshot below is from a study entitled Dimethyl Sulfoxide Damages Mitochondrial Integrity and Membrane Potential in Cultured Astrocytes....

As you can see, DMSO is a neurotoxin. Neurotoxicants are many chemicals or substances that interfere with normal function and/or compromise adaptation in the central and/or peripheral nervous system. DMSO is associated with various central nervous system side effects, such as epileptic seizures, stroke, transient global amnesia, and more. Studies have shown that DMSO can produce widespread apoptosis in the developing central nervous system. If somebody is poisoned with COVID-19 technology or shedding, DMSO is a wrong and potentially dangerous treatment.

Pine bark

If you’re using or considering DMSO, please use pine bark tablets instead and avoid chemical exposure. The entire pine tree is highly medicinal. I use pine needle essential oil and turpentine, 100% pure gum spirits from pine sap, to cleanse parasites with my clients....

Conclusion

If this information doesn't make you angry, it should. Methylene blue and EDTA Acid infusions were sold to the public by fringe doctors as a treatment against COVID-19 graphene oxide nanocomposites and quantum dots. In actuality, they're a crucial part of the operating system, activating and enabling transfection and preserving spike protein production.

It's not necessary to risk your health with unapproved industrial poisons that are genotoxic, neurotoxic, and impossible for our bodies to detox without the help of natural medicinal protocols. We have potent heavy metal chelators that are superior, without toxic risks....)

Expand full comment
A Midwestern Doctor's avatar

Sorry just saw this.

1) Pine bark oil has a much higher toxicity than DMSO (going off LD50).

2) DMSO is not made from pine bark. It was a byproduct of a wood pulping process, but once they realized DMSO had medical properties, they switched to a completely differenty synthesis process to have a higher purity.

3) The article she wrote included an affiliate link to sell her pine bark oil. So she used a fairly classic internet marketing strategy: drum up fear, present a better product, entice people to buy it so she gets $. After talking to her for a bit, I realized she was not willing to change her position at all because doing so would cost her money.

4) The benefits from pine oil are completely different (and much less) than what is seen with DMSO.

5) The studies that show DMSO harms cells are holding them in DMSO at high concenrations for prolonged periods which will never be seen in the body, and at which most substances are highly neurotoxic. In give or take all the studies I've looked at, DMSO is at least 100 times less toxic to cells (by concentrations) than most commonly used supplements or drugs. For example, some studies show DMSO harms mitochondria if they are kept in 1-5% DMSO for 48 hours, but to have that concentration within the body, you would need to drink a liter per day of it, which is at least 100x what people ever consume.

RebeccaStar's avatar

Dear MWD

What do you say about this article??? Is this true? I just started using DMSO on my thumb joints. It is a miracle. Stopped the pain I had almost immediately & I could use my hands all afternoon whereas before the pain was so bad I couldn’t sleep. But I don’t want to get central nervous system side effects! HELP!!!

A Midwestern Doctor's avatar

Sorry just saw this.

1) Pine bark oil has a much higher toxicity than DMSO (going off LD50).

2) DMSO is not made from pine bark. It was a byproduct of a wood pulping process, but once they realized DMSO had medical properties, they switched to a completely differenty synthesis process to have a higher purity.

3) The article she wrote included an affiliate link to sell her pine bark oil. So she used a fairly classic internet marketing strategy: drum up fear, present a better product, entice people to buy it so she gets $. After talking to her for a bit, I realized she was not willing to change her position at all because doing so would cost her money.

4) The benefits from pine oil are completely different (and much less) than what is seen with DMSO.

5) The studies that show DMSO harms cells are holding them in DMSO at high concenrations for prolonged periods which will never be seen in the body, and at which most substances are highly neurotoxic. In give or take all the studies I've looked at, DMSO is at least 100 times less toxic to cells (by concentrations) than most commonly used supplements or drugs. For example, some studies show DMSO harms mitochondria if they are kept in 1-5% DMSO for 48 hours, but to have that concentration within the body, you would need to drink a liter per day of it, which is at least 100x what people ever consume.

Noni Bird's avatar

I read this as well and posted this same article. I am wondering what the MWD will say about this.

A Midwestern Doctor's avatar

Sorry just saw this.

1) Pine bark oil has a much higher toxicity than DMSO (going off LD50).

2) DMSO is not made from pine bark. It was a byproduct of a wood pulping process, but once they realized DMSO had medical properties, they switched to a completely differenty synthesis process to have a higher purity.

3) The article she wrote included an affiliate link to sell her pine bark oil. So she used a fairly classic internet marketing strategy: drum up fear, present a better product, entice people to buy it so she gets $. After talking to her for a bit, I realized she was not willing to change her position at all because doing so would cost her money.

4) The benefits from pine oil are completely different (and much less) than what is seen with DMSO.

5) The studies that show DMSO harms cells are holding them in DMSO at high concenrations for prolonged periods which will never be seen in the body, and at which most substances are highly neurotoxic. In give or take all the studies I've looked at, DMSO is at least 100 times less toxic to cells (by concentrations) than most commonly used supplements or drugs. For example, some studies show DMSO harms mitochondria if they are kept in 1-5% DMSO for 48 hours, but to have that concentration within the body, you would need to drink a liter per day of it, which is at least 100x what people ever consume.

Christian Hendle's avatar

Dr MWD. do you see any benefits or mechanism of action whereby DMSO would help increase red blood cell count and therefore haemoglobin levels in MDS ( myelodysplastic syndrome)?

Bob's avatar

Serious question Doc.

First of all, thank you very much for all of your work

If you were taking different things for prevention of getting sick, would you opt to go to the doctor for any blood tests, scans etc to make sure you are not sick?

Going to my primary care doc scares me.

It looked like a fortress during covid, never seen this doctor yet, so I know his and my point of views dont align at all.

I see a lot of people in different groups asking the same thing, dont go and maintain a healthy lifestyle, take prevention supplements and hope for the best

Or go and get caught up in the machine

Thank you

A Midwestern Doctor's avatar

My situation is different because I know how to treat most illnesses myself and how to recognize medical emergencies. This is a very broad question, so I have no way to soundbite it. I've been trying to get some other authors in the field to write an article on this subject (as I have so many other topics I'm behind on), but thusfar none of them have.

Carolyn Hudson's avatar

Can DMSO topically help Lupus?

Jean Sikkema's avatar

I am having a hard time navigating this as I am new to substack, if I’m at the right place can you please recommend an ORAL DMSO and where to buy it , also how to use it as an ovarian cancer patient. I have quit chemo after 5 of 6 sessions and am doing alternative methods now. Thank you

Quiche's avatar

When DMSO is applied topically, how do you suggest cleaning the skin before application?

Bob's avatar

I wonder if you buy the raw ingredients and make your own extract to make hematoxylin?

Has anybody tried it?

Bob's avatar

Thank you for all you do Doc!!!

Gary Eyre's avatar

Since I am unable to access IV DMSO directly, and since DMSO is suggested to be used directly on the head for a stroke, I'm wondering if there is any research of applying DMSO directly over the heart to accomplish the following:

1) help with heart conditions directly;

2) get the DMSO to the entire body through the blood supply to help with any condition

and 3) for strokes specifically, to treat both hemorrhagic and clot strokes?

Also, do you have a preferred source for hematoxalyn?

Joanne Shannon's avatar

How is the German brand Heiltropfen DMSO?

Jenga's avatar

Does anyone have recommended treatments for ringworm on the body? DMSO doesn't seem to help.

Rachel Stevens's avatar

You might check into a topical ivermectin for ringworm. It works topically for head lice and can be bought retail in stores like Walmart.

Bob Klonoff's avatar

Question regarding sourcing Hematoxylin without added metal salts: According to Copilot AI, Hematoxylin certified by the Biological Stain Commission may contain metal salts such as aluminum or iron to enhance staining properties. Where can one purchase pure hematoxylin?

Lance Grindle's avatar

It is my understanding that the Hematoxylin certified by the New York Biological Stain Commission should be just Hematoxylin. Metal salts, if present, are added by others to the Hematoxylin after they dispatch it.

Sally's avatar

Thank you Dr. Grindle!

Holly Van's avatar

You talked about ozone eliminating the dye’s color. I found the same thing with methylene blue. I had always been intrigued by that finding.

A Midwestern Doctor's avatar

When methylene blue is reduced, it's colorless, when oxidized it's blue. It should become blue with ozone.

Holly Van's avatar

I see. It was in a gallon of ozonated water.

Kit Burke's avatar

My brother has been suffering with pressure from an arachnoid cyst in the third ventricle. Doctors don’t want to operate, some say it’s too small to be causing his symptoms which are a feeling of constant pressure in his head leading to migraine-like headaches with vomiting. He is 70 now and this started as a teenager. A 40-day water fast gave him total relief for about 11 years. He did the fast about 30 years ago. He’s unable to do anything like that now, but I have suggested a ketogenic diet. I think he would be willing to try painting DMSO on his head and or taking orally. Any suggestions? Also, I would love a suggestion as to where to buy an appropriate natural-bristle brush

paws's avatar

In a pinch I find it effective for migraine by pouring tiny amount to cotton ball or in hand and massaging into scalp, neck, temple, wherever it's most located. Also can get 'migraine relief cap' off Amazon that's kept in freezer, major immediate help.

Kit Burke's avatar

Thank you Paws. I appreciate your feedback

paws's avatar

ty, forgot to note I do not use both at same time, as my memory is AMD noting to only use cotton fabric over a dmso-applied area.

Kathie's avatar

This is fascinating.. Thank you :) Maybe someone asked this already.. can it be used as preventative measure?

A Midwestern Doctor's avatar

Quite possibly but no one to my knowledge has tried that (other than to prevent the recurrence of a cancer they already had)

Kathie's avatar

Thanks, I guess that is kinda a dumb question.. :) I try my best to not go anywhere near the Med establishment ( unless I had a Doc like you ) .. I am so glad I subscribed, what a wealth of information you're sharing... Thank you very much.

I was wondering if you have read the Salt Fix?

Another eye opener.

Staci Owen's avatar

My 11 year old grandson has hereditary multiple osteochondroma. Do you know if applying dmso topically may help dissolve these growths on his joints? He was diagnosed at 2 1/2. (Note, drs said one parent would have it for him to have it- but neither does). My daughter thinks it could have been human dna cells in a vaccine. Your thoughts would be so appreciated.

A Midwestern Doctor's avatar

It has worked on FOP, so it might help, but I have no examples to go off.

AJ's avatar

I have a relative with terrible tumor pain on high opiate dose (fentanyl, OxyContin) and ibuprofen. I would do much like to use DMSO but have been told it is dangerous to use when taking opiates. Does anyone know if it might be safe to put just a few drops over the spot where the tumor presses on the sacral bone and causes compression of the s2 nerves and osteomyelitis?

A Midwestern Doctor's avatar

The main drugs DMSO had been identifed to potentiate were benzodiazepines and alcohol. When DMSO is applied topically in a region, there is a relatively small risk for a potentiation effect. Also in the DMSO bicarbonate studies, the patients were on IV DMSO and opiods and did not have issues (rather they stopped needing the opioids).

Bevo's avatar

Hi any known suppliers of DMSO in Australia?

Bevo's avatar

Thanks for the links. The DMSO Store doesn't seem to post to Aust....I'll try Amazon.

Cheers.

ComeQuicklyLord's avatar

Off topic: I have been trying to find the studies Dr. Paul Marik had on Vitamin C protocol for Sepsis, but I do not have access to those published studies. Can you provide those studies?

I’m interested in the specific dosages he used for Vitamin C, hydrocortisone, and thiamine.

I’m thinking about putting this on my Advanced Directive in case I’m hospitalized and going into Sepsis.

This article is extremely practical. May be RFK can open up avenues for DMSO and other alternative methods for health.

ComeQuicklyLord's avatar

As a side note, my doctor said I should not apply DMSO on my knee that had a total replacement—it evidently can deteriorate the device.

Am I correct in assuming that I can use it on my back and elsewhere, and it will not affect my device?

Also, to dilute DMSO, I need to use distilled water, but they come in plastic bottles. Is that a problem?

A Midwestern Doctor's avatar

1) Yes.

2) That would depend on the materials in the TKA (ie. DMSO will not dissolve knees). The only place I've seen DMSO thusfar cause issues with medical material in the body were for certain types of dental implants.

Glynda's avatar

I have a titanium dental post on rear molar. Will DMSO deteriorate the post? I have been swabbing a small amount of DMSO on the surrounding gums due to a long standing warm pain around the implant which has been dentally blessed as a non problem.

D_Collins's avatar

The better outcome of cancer patients who have not had chemotherapy versus those who have had it struck me when you mentioned it. I understand from my reading that chemotherapy tends to stimulate and release cancer stem cells (CSCs). Perhaps the D-Hematoxylin eliminates those from the tumor along with the rest of the cancer cells, so that subsequent chemotherapy doesn't generate them. This would explain the long survival times of some of these patients.

A Midwestern Doctor's avatar

This is also observed with a lot of other natural therapies used to treat cancer.

Quiche's avatar

Is it possible to find the book with John L. Sessions anywhere?

A Midwestern Doctor's avatar

There isn't much in it on the subject other than that it showed someone besides Tucker used D-hematoxylin

Mindy Jones's avatar

Any evidence DMSO is effective for recurrent abdominal ascites in a pancreatic cancer patient? Started after 5 weeks of radiation.

Bobbi's avatar

Just wanted to check are there any dosage restrictions in renal failure - especially pediatric? Thank you

Pam's avatar

Can DMSO be used for scalp psoriasis? And, can it be used with something else?

pimaCanyon's avatar

Dr. Makis has posted article re patients successfully treating psoriasis with Ivermectin.

FREED0ML0VER's avatar

"Still, many understandably started with a high dose as they did not want to wait for the results, a few of whom then shared they’d had a skin reaction..." What type of skin reaction specifically?

A Midwestern Doctor's avatar

Rash and irritiation. Nothing severe

Isaiah Antares's avatar

Interesting side note: I experienced some skin irritation (a mild rash) from it just today, after weeks of using it without incident. I think it was due to me using a fan on it while it was drying.

I wasn't trying to make it dry faster; the fan just seemed to help ease the stinging (I'm using ultra-pure liquid). But it seemed to create a negative side effect. Maybe it caused it to dry too fast, or not absorb fully? No idea.

As stated, it is mild; but I advise against fans.

Fun fact: you mentioned that the face is especially sensitive, but I've never felt any pain when using it there. It's way worse on my torso.

Old_Mainer's avatar

Another blockbuster article. I am particularly interested because I have had chronic lymphocytic leukemia for 27 years. Question: For strictly transdermal use is it possible that the raw hematoxylin can be sterilized by heat rather than ozone? Or not sterilized at all?

wns115's avatar

My father was diagnosed with leukemia 6 years ago. I took him to Hippocrates Health Institute (HHI) and he did the 3-week program. He returned home with no leukemia. He is now 92 years old.

I cannot guarantee that it would help your situation but thought I would share. HHI says that 'blood' cancers are among the easiest to heal from. The challenge occurs when it moves into organs and bones.

Mouzer's avatar

I just saw a reply above that the steralization is not needed if on the skin.

Lance Grindle

Lance Grindle

1m

No. Not necessary. There is no need to do sterilization process of that part of the process

if it is not going to be used i.v. Rectal also is note needed. Simply mix and apply.

Any questions about preparation, proporciones, administration or other of D-Hematoxylin

anyone in this chat I would be more than happy to answer. Dr Grindle

Old_Mainer's avatar

So, if I understand you correctly, all that is strictly necessary for transdermal application is to oxidize the hematoxylin with ozone and mix it with DMSO at MWD's proportions. The resulting paste/slurry could be filtered through a coffee filter to remove the gross particles and the filtrate be applied directly to the skin straight or diluted. Correct? Thank you so much for your help.

A Midwestern Doctor's avatar

It will oxidize once inside the body.

Old_Mainer's avatar

So much for the oxidation problem, per MWD. The next quandry is that hematoxylin is available in a variety of colors and grades - pharmaceutical not being one of them. Per the MSDS pure hematoxylin is white to pale yellow. The Chemsavers brand on Amazon is stated to be 60% pure and is pictured as pale yellow. (However the webpage address includes "Hematoxylin-Natural-Black") It is $88.95 for 25g. A second brand, Akersunder, is stated to be 99+% pure, with the color unspecified. It is $250 for 25g. There are multiple other brands with unstated color or purity. Anyone have more information?

Mouzer's avatar

I am repeating what the doctor posted. At the top of the comments he said you can contact him. He coauthored the article.

Bob's avatar

So if ozone is not needed to oxidize, could heating the powder to 100C for a few minutes be used to sterilize for intravesical application, and what would be the dilution for intravesical application for prostate cancer?

Mouzer's avatar

I reposted a reply from Lance Grindle because, at the time, the comments were coming fast and furious and the other person missed it as the layers got so long and deep. I suggest you find one of Grindle's comments and repost this under it, though I don't know if he still is on substack. Sorry, I can't answer this.

Bob's avatar

Thanks - just learning to navigate substack, so this is helpful.

Mouzer's avatar

There are multiple ozone generators that are within the average person's price range. I imagine one would somehow enclose the area where the ozone is generated (like a small box over it and the hematoxylin) to get the best effect. There are different kinds of hematoxylin. I didn't get from the article which, if one is better, is the best choice.

Mouzer's avatar

I don't know. Sounds like that institute mentioned would be a good choice. Could be some Chem major in university might do the prep for a fee. I just would be circumspect why you want it done.

Robert's avatar

biology major more likely, or biochem. Not chemistry.

Old_Mainer's avatar

Most ozone generators produce a diffuse flow through a grill.

here is a reasonably priced one that flows out of a flexible tube:

https://www.amazon.com/Airthereal-AH1000-Portable-Machine-Liquid/dp/B08YDCZVDD/ref=sr_1_4?

Zade's avatar

I bought some 99.995% pure on Amazon. Not too expensive. Multiple vendors and purities on Amazon alone.

Sagaface's avatar

Will you be investigating ways to ameliorate the smell? I’m extremely sensitive. Thank you for your incredible work.

Christina's avatar

I find mixing it with honey helps. I do 7 parts 99% pure DMSO, 3 parts water, and one part honey. It can be used orally or topically.

Nj's avatar

Thanks Christina! I've got some 99% pure dsmo, but haven't found anyone telling me how to use or mix it! Does it have to be mixed in glass container or can you use plastic spray bottle? My DSMO has a dropper. So do I just measure it into a teaspoon? Plastic or metal? Hope I see your answer!

Christina's avatar

There are directions for use at the end of some of A Midwestern Doctor's articles, but that part, I believe, is behind the paywall, so I am not going to make those available here in the comment section. Glass has the advantage over plastic because DMSO will not dissolve glass but will dissolve some types of plastic. In theory, a solvent-resistent plastic should be OK, but in real life, who knows? I would use stainless steel measuring spoons; the plastic sorts would probably slowly dissolve. I would not recommend spray bottles either for the same reason.

Go west's avatar

My bil had success with chlorella